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TAF2N; TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56) (17q11.1-q11.2)
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    Summary Information - TAF2N
    Gene Database Entries for TAF2N
    Other TAF2N Related Resources
    TAF2N -Defining Texts
    t(9;17)(q22;q11) in Extraskeletal Myxoid Chondrosarcoma
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  Summary Information

TAF2N; TATA box binding protein (TBP)-associated factor, RNA polymerase II, N, 68kD (RNA-binding protein 56)

Location: 17q11.1-q11.2
Alias: RBP56

Overview: TAF2N was identified in 1996 on the basis of its partial homology to the EWS and FUS genes which are frequently involved in translocations in human sarcomas. A subset of extraskeletal myxoid chondrosarcomas have t(9;17)(q22;q11) involving the TAF2N and NR4A3 (CHN) genes.

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  Gene Database Entries for TAF2N

OMIM
GeneCard (Weizmann Institute)
Genbank
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for TAF2N)

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  Other Related Resources

Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (TAF2N[TI] OR RBP56[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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      TAF2N -Defining Texts

  • Morohoshi F, et al Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins. Genomics 1996 Nov 15;38(1):51-7    Related articles (PubMed)

  • Medline Search: taf2n OR rbp56 (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

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  •   t(9;17)(q22;q11) in Extraskeletal Myxoid Chondrosarcoma

  • Attwooll C, et al. Identification of a novel fusion gene involving hTAFII68 and CHN from a t(9;17)(q22;q11.2) translocation in an extraskeletal myxoid chondrosarcoma. Oncogene 1999 Dec 9;18(52):7599-601    Related articles (PubMed)

  • Panagopoulos I, et al. Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11). Oncogene 1999 Dec 9;18(52):7594-8    Related articles (PubMed)

  • Bjerkehagen B, et al. Extraskeletal myxoid chondrosarcoma: multimodal diagnosis and identification of a new cytogenetic subgroup characterized by t(9;17)(q22;q11). Virchows Arch 1999 Nov;435(5):524-30    Related articles (PubMed)

  • Sjogren H, et al. Fusion of the EWS-related gene TAF2N to TEC in extraskeletal myxoid chondrosarcoma. Cancer Res 1999 Oct 15;59(20):5064-7    Related articles (PubMed)

  • Medline Search: extraskeletal myxoid chondrosarcoma AND translocation AND chromosome 17 (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Chondrosarcoma Genetics
    Chondrosarcoma : Clinical and Epidemiological Information

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