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COT; COT (cancer Osaka thyroid) oncogene (10p11.2)
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    Summary Information - COT
    Gene Database Entries for COT
    Other COT Related Resources
    COT and Cancer
    COT Over Expression and Amplification in Breast Cancer
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  Summary Information

COT; COT (cancer Osaka thyroid) oncogene

Location: 10p11.2

Aliases: MAP3K8, TPL-2

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  Gene Database Entries for COT

OMIM
GeneCard (Weizmann Institute)
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for COT)

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  Other Related Resources

Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (COT[TI] OR MAP3K8[TI] OR TPL-2[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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      COT and Cancer

  • Chan AM, et al. Expression cDNA cloning of a serine kinase transforming gene. Oncogene 1993;8(5):1329-33    Related articles (PubMed)

  • Tsatsanis C, Spandidos DA The role of oncogenic kinases in human cancer. [Review] Int J Mol Med 2000;5(6):583-90    Related articles (PubMed)

  • Tsatsanis C, et al. Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB. Oncogene 1998 Nov 19;17(20):2609-18    Related articles (PubMed)

  • Ohara R, et al. Identification of the cells expressing cot proto-oncogene mRNA. J Cell Sci 1995;108 ( Pt 1):97-103    Related articles (PubMed)

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  •   COT Over Expression and Amplification in Breast Cancer

  • Sourvinos G, et al. Overexpression of the Tpl-2/Cot oncogene in human breast cancer. Oncogene 1999 Sep 2;18(35):4968-73    Related articles (PubMed)

  • Medline Search: breast cancer AND (cot OR tpl-2) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Breast Cancer Genetics
    Breast Cancer : Clinical and Epidemiological Information

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