EMS1 - EMS1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate))

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EMS1; EMS1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate)) (11q13)
EMS1 Menu Summary Information - EMS1 Gene Database Entries for EMS1 Other EMS1 Related Resources EMS1 and Cancer (general) - Amplification of the 11q13 region and Prognosis EMS1 and Breast Cancer EMS1 and Other Cancers Feedback / suggest a new topic for EMS1
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Summary Information
EMS1; EMS1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate)) Location: 11q13 Overview: Chromosome 11q13 amplification is frequently found in certain cancers; particularly in breast cancer (approx 13%) and head and neck cancers (approx 29%). The amplified 11q13 region includes EMS1 and many other candidate genes which may or may not have a primary role in carcinogenesis. Return to EMS1 Contents
Gene Database Entries for EMS1
OMIM GeneCard (Weizmann Institute) Tumor Gene Database Genbank Locus Link UniGene GenAtlas GDB Nomenclature (search for EMS1) Return to EMS1 Contents
Other Related Resources
Search Medline for related articles (PubMed) *Medline Search:* cancer AND gene AND EMS1[TI] (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to EMS1 Contents
EMS1 and Cancer (general)
Schuuring E. et al. Characterization of the EMS1 gene and its product, human Cortactin. Cell Adhes Commun 1998; 6:185-209 Related articles (PubMed) Schuuring E. et al. Identification and cloning of two overexpressed gene U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas. Oncogene 1992; 7:355-61 Related articles (PubMed) van Damme H. et al. The redistribution of cortactin into cell-matrix contact sites in human carcinoma cells with 11q13 amplification is associated with both overexpression and post-translational modification. J Biol Chem 1997; 272:7374-80 Related articles (PubMed) *Medline Search:* EMS1 AND gene AND cancer (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to EMS1 Contents
Amplification of the 11q13 region and Prognosis
Schuuring E. et al Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer. Cancer Res 1992; 52:5229-34 Related articles (PubMed) Meredith SD et al. Chromosome 11q13 amplification in head and neck squamous cell carcinoma. Association with poor prognosis. Arch Otolaryngol Head Neck Surg 1995; 121:790-4 Related articles (PubMed) *Medline Search:* chromosome 11 AND breast cancer AND prognosis (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to EMS1 Contents
EMS1 and Breast Cancer
Hui R. et al. EMS1 gene expression in primary breast cancer: relationship to cyclin D1 and oestrogen receptor expression and patient survival. Oncogene 1998; 17:1053-9 Related articles (PubMed) Hui R, et al. EMS1 amplification can occur independently of CCND1 or INT-2 amplification at 11q13 and may identify different phenotypes in primary breast cancer. Oncogene. 1997; 15:1617-23 Related articles (PubMed) *Medline Search:* EMS1 AND breast cancer (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources Breast Cancer Genetics Breast Cancer : Clinical and Epidemiological Information Return to EMS1 Contents
EMS1 and Other Cancers
Bringuier PP. et al. Expression of cyclin D1 and EMS1 in bladder tumours; relationship with chromosome 11q13 amplification. Oncogene 1996; 12:1747-53 Related articles (PubMed) *Medline Search:* EMS1 AND gene AND cancer (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to EMS1 Contents
[Home] This page created: 09/10/1999 Last revised: 29/04/2003 © Copyright 1999-

EMS1; EMS1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate))