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Menu: Gene Databases

General Genome Databases

Specialist Cancer Genetics Databases

General Genome Databases (9 links)

• GeneCards (Weizmann Institute of Science, Israel) includes summary information and links for each gene.
• BCM Search Launcher - Baylor College of Medicine (USA) This site provides a single point-of-entry for sequence searches accross molecular biology-related search and analysis services available on the WWW. Searches include multiple and pairwize sequence alignments.
• GDB - Genome Database (Human Genome Project) database of the international collaborative project established in 1990.
• Nomenclature Nomenclature database of the HUGO Nomenclature Committee
• LocusLink (National Center for Biotechnology Information, USA)
• Online Mendelian Inheritance in Man (OMIM) (National Center for Biotechnology Information, USA) a searchable database which catalogues human genes and genetic disorders with links to Medline Citations.
• Database of Single Nucleotide Polymorphisms (National Center for Biotechnology Information) A public database of single base nucleotide substitutions and short deletion and insertion polymorphisms. Users can search for and submitt SNPs.
• Unigene (National Center for Biotechnology Information, USA)
• Universal Mutation Database (INSERM) French Institute of Health and Medical Research

Molecular Biology Databases

Specialist Cancer Genetics Databases (10 links)

• Tumor Gene Database (Baylor College of Medicine)
• p53 Web site of the Institute Curie This includes a extensive database to which users can add new p53 mutations, search for mutations or run insertion or deletion analysis tools. There are also statistical tools and detailed references.
• Mouse Tumor Biology Databases (MTB) This is database is maintained by the Jackson Laboratory and is funded by the NCI. Data is available by tumour and tissue type, with information on pathology and mice strains to facilitate the mouse as a model system of hereditary cancer.
• IARC database of Somatic P53 Mutations in Human Tumours and Cell Lines (IARC) Web interface or download.
• Atlas of Genetics and Cytogenetics in Oncology and Haematology (Poitiers University, France) a collaborative site made for and by cytogeneticists, molecular biologists, oncologists etc. Databases of genes, cytogenetic abnormalities, disease types, and cancer prone conditions. English and French language.
• Androgen Receptor Gene Mutations Database (McGill University, Montreal, Canada) a database of AR mutations, map of AR interacting proteins, mutations map for prostate cancer, online forum and links.
• Cancer Genome Anatomy Project / Database (National Cancer Institute + partners) aims to establish complete index of genes expressed in tumors. A growing database sorted by anatomical site, from which gene sequences can be downloaded. It includes details of reagents and methodology.
• International NF1 Genetic Mutation Analysis Consortium The consortium was established in 1992 and is managed by Dr Bruce Korf, Harvard Medical School, USA. The site is intended for scientists and a password is required to access the database.
• Hereditary Non-Polyposis Colorectal Cancer - Mutation Databases (International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer) includes databases of MLH1, MSH2, MSH6, PMS1 and PMS2 mutations.
• Breast Cancer Information Core An on-line breast cancer mutation database. This is an international collaboration hosted by the NIH National Human Genome Research Institute. The Web site includes the database (requires registration), laboratory methods, forum and resources.