Summary Information - PI5 Gene Database Entries for PI5 Other PI5 Related Resources Maspin and Breast Cancer Maspin and Prostate Cancer Maspin - Role in Angiogenesis Inhibition ? Feedback / suggest a new topic for PI5
PI5; Protease inhibitor 5 (maspin) Location: 18q21.3 Alias: maspin Tumour supressor and angiogenesis inhibitor Return to PI5 Contents
Location: 18q21.3 Alias: maspin
Tumour supressor and angiogenesis inhibitor
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OMIM GeneCard (Weizmann Institute) Genbank Swiss-Prot Locus Link (search for PI5) UniGene GenAtlas GDB (search for PI5) Nomenclature (search for PI5) Return to PI5 Contents
Search Medline for related articles (PubMed) Medline Search: cancer AND gene AND (PI5[TI] OR maspin[TI]) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to PI5 Contents
Zou Z, et al. Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells. Science. 1994; 263(5146):526-9 Related articles (PubMed) Seftor RE, et al. maspin suppresses the invasive phenotype of human breast carcinoma. Cancer Res. 1998; 58(24):5681-5 Related articles (PubMed) Related Resources Breast Cancer Genetics Breast Cancer : Clinical and Epidemiological Information Return to PI5 Contents
Zhang M, et al. Expression of maspin in prostate cells is regulated by a positive ets element and a negative hormonal responsive element site recognized by androgen receptor. Proc Natl Acad Sci USA. 1997; 94(11):5673-8 Related articles (PubMed) Sheng S, et al. Maspin acts at the cell membrane to inhibit invasion and motility of mammary and prostatic cancer cells. Proc Natl Acad Sci USA. 1996; 93(21):11669-74 Related articles (PubMed) Related Resources Prostate Cancer Genetics Prostate Cancer : Clinical and Epidemiological Information Return to PI5 Contents
Zhang M, et al. Maspin is an angiogenesis inhibitor. Nat Med 2000; 6(2):196-199 Related articles (PubMed) Medline Search: maspin AND angiogenesis (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to PI5 Contents
PI5; Protease inhibitor 5 (maspin) (18q21.3)
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Breast Cancer Genetics