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Recent Publications

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Krona C, et al.
Screening for gene mutations in a 500 kb neuroblastoma tumor suppressor candidate region in chromosome 1p; mutation and stage-specific expression in UBE4B/UFD2.
Oncogene 2003 Apr 17;22(15):2343-51    [Related articles]
     Screening
Stallings RL, et al.
Are gains of chromosomal regions 7q and 11p important abnormalities in neuroblastoma?
Cancer Genet Cytogenet 2003 Jan 15;140(2):133-7    [Related articles]
Hogarty MD, et al.
No evidence for the presence of an imprinted neuroblastoma suppressor gene within chromosome sub-band 1p36.3.
Cancer Res 2002 Nov 15;62(22):6481-4    [Related articles]
Van Roy N, et al.
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two..
Genes Chromosomes Cancer 2002 Oct;35(2):113-20    [Related articles]
     Chromosome 17q
Spitz R, et al.
Fluorescence in situ hybridization analyses of chromosome band 1p36 in neuroblastoma detect two classes of alterations.
Genes Chromosomes Cancer 2002 Jul;34(3):299-305    [Related articles]
Godfried MB, et al.
Lack of interstitial chromosome 1p deletions in clinically-detected neuroblastoma.
Eur J Cancer 2002 Jul;38(11):1513-9    [Related articles]
Skog J, et al.
Human adenovirus serotypes 4p and 11p are efficiently expressed in cell lines of neural tumour origin.
J Gen Virol 2002 Jun;83(Pt 6):1299-309    [Related articles]
Mora J, et al.
Evolving significance of prognostic markers associated with treatment improvement in patients with stage 4 neuroblastoma.
Cancer 2002 May 15;94(10):2756-65    [Related articles]
     MYCN Amplification Chromosome 17q
Teitz T, et al.
Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN.
Oncogene 2002 Mar 14;21(12):1848-58    [Related articles]
     MYCN Amplification
Abel F, et al.
Analyses of apoptotic regulators CASP9 and DFFA at 1P36.2, reveal rare allele variants in human neuroblastoma tumours.
Br J Cancer 2002 Feb 12;86(4):596-604    [Related articles]
De Toledo M, et al.
The gene for a new brain specific RhoA exchange factor maps to the highly unstable chromosomal region 1p36.2-1p36.3.
Oncogene 2001 Nov 1;20(50):7307-17    [Related articles]
Huang S, et al.
Reassignment of the EPB4.1 gene to 1p36 and assessment of its involvement in neuroblastomas.
Eur J Clin Invest 2001 Oct;31(10):907-914    [Related articles]
Yang HW, et al.
Genomic structure and mutational analysis of the human KIF1B gene which is homozygously deleted in neuroblastoma at chromosome 1p36.2.
Oncogene 2001 Aug 16;20(36):5075-83    [Related articles]
Chen YZ, et al.
Homozygous deletion in a neuroblastoma cell line defined by a high-density STS map spanning human chromosome band 1p36.
Genes Chromosomes Cancer 2001 Aug;31(4):326-32    [Related articles]
Anderson J, et al.
Neuroblastoma in monozygotic twins--a case of probable twin-to-twin metastasis.
Br J Cancer 2001 Aug 17;85(4):493-6    [Related articles]
     MYCN Amplification
Bauer A, et al.
Smallest region of overlapping deletion in 1p36 in human neuroblastoma: A 1 Mbp cosmid and PAC contig.
Genes Chromosomes Cancer 2001 Jul;31(3):228-39    [Related articles]
Spieker N, et al.
Three chromosomal rearrangements in neuroblastoma cluster within a 300-kb region on 1p36.1.
Genes Chromosomes Cancer 2001 Jun;31(2):172-81    [Related articles]
Lastowska M, et al.
Comprehensive genetic and histopathologic study reveals three types of neuroblastoma tumors.
J Clin Oncol 2001 Jun 15;19(12):3080-90    [Related articles]
     MYCN Amplification Chromosome 17q
Gaitanou M, et al.
Cloning, expression and localization of human BM88 shows that it maps to chromosome 11p15.5, a region implicated in Beckwith-Wiedemann syndrome and tumorigenesis.
Biochem J 2001 May 1;355(Pt 3):715-24    [Related articles]
Wei Yang H, et al.
Dna fragmentation factor 45 (dff45) gene at 1p36.2 is homozygously deleted and encodes variant transcripts in neuroblastoma cell line.
Neoplasia 2001 Mar-Apr;3(2):165-9    [Related articles]
Caron H, et al.
Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted.
Genes Chromosomes Cancer 2001 Feb;30(2):168-174    [Related articles]
Blatt J
Tumor suppressor genes on the short arm of chromosome 1 in neuroblastoma.
Pediatr Hematol Oncol 2001 Jan-Feb;18(1):3-5    [Related articles]
White PS, et al.
Detailed molecular analysis of 1p36 in neuroblastoma.
Med Pediatr Oncol 2001 Jan;36(1):37-41    [Related articles]
Vandesompele J, et al.
Multicentre analysis of patterns of DNA gains and losses in 204 neuroblastoma tumors: how many genetic subgroups are there?
Med Pediatr Oncol 2001 Jan;36(1):5-10    [Related articles]
     MYCN Amplification Chromosome 17q
Thompson PM, et al.
Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.
Cancer Res 2001 Jan 15;61(2):679-86    [Related articles]
Schilling FH, et al.
Absence of somatostatin receptor expression in vivo is correlated to di- or tetraploid 1p36-deleted neuroblastomas.
Med Pediatr Oncol 2001 Jan;36(1):56-60    [Related articles]
Maris JM, et al.
Comprehensive analysis of chromosome 1p deletions in neuroblastoma.
Med Pediatr Oncol 2001 Jan;36(1):32-6    [Related articles]
Ladenstein R, et al.
Prognostic significance of DNA di-tetraploidy in neuroblastoma.
Med Pediatr Oncol 2001 Jan;36(1):83-92    [Related articles]
     MYCN Amplification
Ichimiya S, et al.
Genetic analysis of p73 localized at chromosome 1p36.3 in primary neuroblastomas.
Med Pediatr Oncol 2001 Jan;36(1):42-4    [Related articles]
Hogarty MD, et al.
Analysis of genomic imprinting at 1p35-36 in neuroblastoma.
Med Pediatr Oncol 2001 Jan;36(1):52-5    [Related articles]
Hiyama E, et al.
Biological characteristics of neuroblastoma with partial deletion in the short arm of chromosome 1.
Med Pediatr Oncol 2001 Jan;36(1):67-74    [Related articles]
Ejeskar K, et al.
Fine mapping of a tumour suppressor candidate gene region in 1p36.2-3, commonly deleted in neuroblastomas and germ cell tumours.
Med Pediatr Oncol 2001 Jan;36(1):61-6    [Related articles]
Ambros PF, et al.
Intratumoural heterogeneity of 1p deletions and MYCN amplification in neuroblastomas.
Med Pediatr Oncol 2001 Jan;36(1):1-4    [Related articles]
     MYCN Amplification
Ambros PF, et al.
Intratumoural heterogeneity of 1p deletions and MYCN amplification in neuroblastomas.
Med Pediatr Oncol 2001 Jan;36(1):1-4    [Related articles]
     MYCN Amplification
Nakagawara A, et al.
Identification of the homozygously deleted region at chromosome 1p36.2 in human neuroblastoma.
Med Pediatr Oncol 2000 Dec 1;35(6):516-521    [Related articles]
Hogarty MD, et al.
Identification of a 1-megabase consensus region of deletion at 1p36.3 in primary neuroblastomas.
Med Pediatr Oncol 2000 Dec 1;35(6):512-515    [Related articles]
Benn DE, et al.
Sporadic and familial pheochromocytomas are associated with loss of at least two discrete intervals on chromosome 1p.
Cancer Res 2000 Dec 15;60(24):7048-51    [Related articles]
Ohira M, et al.
Identification and characterization of a 500-kb homozygously deleted region at 1p36.2-p36.3 in a neuroblastoma cell line.
Oncogene 2000 Aug 31;19(37):4302-4307    [Related articles]
Nagai M, et al.
Identification of the full-length KIAA0591 gene encoding a novel kinesin-related protein which is mapped to the neuroblastoma suppressor gene locus at 1p36.2.
Int J Oncol. 2000 May;16(5):907-16.    [Related articles]
Maris JM, et al.
Loss of heterozygosity at 1p36 independently predicts for disease progression but not decreased overall survival probability in neuroblastoma patients: a Children's Cancer Group study.
J Clin Oncol. 2000 May;18(9):1888-99.    [Related articles]
     Trials & Studies
Jogi A, et al.
Patched 2, located in 1p32-34, is not mutated in high stage neuroblastoma tumors.
Int J Oncol. 2000 May;16(5):943-9.    [Related articles]
Spieker N, et al.
An integrated 5-Mb physical, genetic, and radiation hybrid map of a 1p36.1 region implicated in neuroblastoma pathogenesis.
Genes Chromosomes Cancer. 2000 Feb;27(2):143-152.    [Related articles]
Mora J, et al.
Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p.
J Mol Diagn 2000 Feb;2(1):37-46    [Related articles]
Ejeskar K, et al.
Fine mapping of the human preprocortistatin gene (CORT) to neuroblastoma consensus deletion region 1p36.3-->p36.2, but absence of mutations in primary tumors.
Cytogenet Cell Genet 2000;89(1-2):62-6    [Related articles]
Wuyts W, et al.
Refined physical mapping and genomic structure of the EXTL1 gene.
Cytogenet Cell Genet. 1999;86(3-4):267-70.    [Related articles]
Fan YS, et al.
Small terminal deletion of 1p and duplication of 1q: Cytogenetics, FISH studies, and clinical observations at newborn and at age 16 years.
Am J Med Genet. 1999 Sep;86(2):118-123.    [Related articles]
Hadano S, et al.
Genomic organization of the human caspase-9 gene on Chromosome 1p36. 1-p36.3.
Mamm Genome. 1999; 10(7):757-60.    [Related articles]
Olianas MC, et al.
[Phe1phi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 acts as a partial agonist at ORL1 receptor endogenously expressed in mouse N1E-115 neuroblastoma cells.
Neuroreport. 1999 Apr 6;10(5):1127-31.    [Related articles]
Lo Cunsolo C, et al.
Neuroblastoma in two siblings supports the role of 1p36 deletion in tumor development.
Cancer Genet Cytogenet. 1999 Mar;109(2):126-30.    [Related articles]
Kaneko Y, et al.
Disomy 1 with terminal 1p deletion is frequent in mass-screening-negative/late-presenting neuroblastomas in young children, but not in mass-screening-positive neuroblastomas in infants.
Int J Cancer. 1999 Jan 5;80(1):54-9.    [Related articles]
     Screening
Ichimiya S, et al.
p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent.
Oncogene. 1999 Jan 28;18(4):1061-6.    [Related articles]
Komuro H, et al.
Fluorescence in situ hybridization analysis of chromosome 1p36 deletions in human MYCN amplified neuroblastoma.
J Pediatr Surg. 1998 Nov;33(11):1695-8.    [Related articles]
     MYCN Amplification
Da Silva J, et al.
[Oncogenic factors of metastatic dissemination in neuroblastoma].
C R Seances Soc Biol Fil. 1998;192(2):261-71. Review. French.    [Related articles]
Vandesompele J, et al.
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
Genes Chromosomes Cancer. 1998 Oct;23(2):141-52.    [Related articles]
     Chromosome 17q
Sunahara M, et al.
Mutational analysis of the p73 gene localized at chromosome 1p36.3 in colorectal carcinomas. [1p36.3 region also frequently deleted in neuroblastoma]
Int J Oncol 1998 Aug;13(2):319-323    [Related articles]
Grenet J, et al.
Duplication of the DR3 gene on human chromosome 1p36 and its deletion in human neuroblastoma.
Genomics. 1998 May 1;49(3):385-93.    [Related articles]
Gotoh T, et al.
Human neuroblastoma demonstrating clonal evolution in vivo.
Genes Chromosomes Cancer. 1998 May;22(1):42-9.    [Related articles]
     MYCN Amplification
Roberts T, et al.
Molecular characterization of the 1p22 breakpoint region spanning the constitutional translocation breakpoint in a neuroblastoma patient with a t(1;10)(p22;q21).
Cancer Genet Cytogenet. 1998 Jan 1;100(1):10-20.    [Related articles]
Roberts T; Cowell JK; Chernova O Molecular characterization of the 1p22 breakpoint region spanning the constitutional translocation breakpoint in a neuroblastoma patient with a t(1;10)(p22;q21).
Cancer Genet Cytogenet 1998 Jan 1;100(1):10-20
Bieche I, et al.
Deletion mapping in breast tumor cell lines points to two distinct tumor-suppressor genes in the 1p32-pter region, one of deleted regions (1p36.2) being located within the consensus region of LOH in neuroblasto
Oncol Rep. 1998 Jan-Feb;5(1):267-72.    [Related articles]
Bieche I; Lidereau R; Khodja A Deletion mapping in breast tumor cell lines points to two distinct tumor-suppressor genes in the 1p32-pter region, one of deleted regions (1p36.2) being located within the consens
Oncol Rep 1998 Jan-Feb;5(1):267-72
White PS, et al.
Molecular analysis of the region of distal 1p commonly deleted in neuroblastoma.
Eur J Cancer. 1997 Oct;33(12):1957-61.    [Related articles]
Van Roy N, et al.
Analysis of 1;17 translocation breakpoints in neuroblastoma: implications for mapping of neuroblastoma genes.
Eur J Cancer. 1997 Oct;33(12):1974-8.    [Related articles]
     Chromosome 17q
Tonini GP, et al.
Loss of heterozygosity for chromosome 1p in familial neuroblastoma.
Eur J Cancer. 1997 Oct;33(12):1953-6.    [Related articles]
Rubie H, et al.
Loss of chromosome 1p may have a prognostic value in localised neuroblastoma: results of the French NBL 90 Study. Neuroblastoma Study Group of the Societe Francaise d'Oncologie Pediatrique (SFOP).
Eur J Cancer. 1997 Oct;33(12):1917-22.    [Related articles]
Maris JM, et al.
Molecular genetic analysis of familial neuroblastoma.
Eur J Cancer. 1997 Oct;33(12):1923-8.    [Related articles]
Maris JM, et al.
Human Kruppel-related 3 (HKR3): a candidate for the 1p36 neuroblastoma tumour suppressor gene?
Eur J Cancer. 1997 Oct;33(12):1991-6.    [Related articles]
Martinsson T, et al.
Delimitation of a critical tumour suppressor region at distal 1p in neuroblastoma tumours.
Eur J Cancer. 1997 Oct;33(12):1997-2001.    [Related articles]
Avigad S, et al.
Prognostic relevance of genetic alterations in the p32 region of chromosome 1 in neuroblastoma.
Eur J Cancer. 1997 Oct;33(12):1983-5.    [Related articles]
Van Roy N, et al.
Comparative genomic hybridization analysis of human neuroblastomas: detection of distal 1p deletions and further molecular genetic characterization of neuroblastoma cell lines.
Cancer Genet Cytogenet. 1997 Sep;97(2):135-42.    [Related articles]
     Chromosome 17q
Lastowska M, et al.
Gain of chromosome arm 17q predicts unfavourable outcome in neuroblastoma patients. U.K. Children's Cancer Study Group and the U.K. Cancer Cytogenetics Group.
Eur J Cancer. 1997 Sep;33(10):1627-33.    [Related articles]
     Chromosome 17q
Kaghad M, et al.
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.
Cell. 1997 Aug 22;90(4):809-19.    [Related articles]
Ohtsu K, et al.
Clinical Investigation of Neuroblastoma with Partial Deletion in the Short Arm of Chromosome 1.
Clin Cancer Res. 1997 Jul;3(7):1221-1228.    [Related articles]
Plantaz D, et al.
Gain of chromosome 17 is the most frequent abnormality detected in neuroblastoma by comparative genomic hybridization.
Am J Pathol. 1997 Jan;150(1):81-9.    [Related articles]
     Chromosome 17q
Caron H, et al.
Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma.
N Engl J Med. 1996 Jan 25;334(4):225-30.    [Related articles]
O'Leary T, et al.
Loss of heterozygosity at 1p36 predicts poor prognosis in gastrointestinal stromal/smooth muscle tumors.
Lab Invest. 1999 Dec;79(12):1461-7.    [Related articles]
Nomoto S, et al.
Frequent allelic imbalance suggests involvement of a tumor suppressor gene at 1p36 in the pathogenesis of human lung cancers.
Genes Chromosomes Cancer. 2000 Jul;28(3):342-346.    [Related articles]
Mihara M, et al.
Absence of mutation of the p73 gene localized at chromosome 1p36.3 in hepatocellular carcinoma.
Br J Cancer. 1999 Jan;79(1):164-7.    [Related articles]
Koesters R, et al.
Human Eukaryotic Initiation Factor EIF2C1 Gene: cDNA Sequence, Genomic Organization, Localization to Chromosomal Bands 1p34-p35, and Expression.
Genomics. 1999 Oct 15;61(2):210-218.    [Related articles]
Bieche I, et al.
Deletion mapping of chromosomal region 1p32-pter in primary breast cancer.
Genes Chromosomes Cancer. 1999 Mar;24(3):255-63.    [Related articles]

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First created: 10/01/99
Last Modified: 20/07/2003