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NBL1; Neuroblastoma candidate region, suppression of tumorigenicity 1 (1p36)
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NBL1; Neuroblastoma candidate region, suppression of tumorigenicity 1

Location: 1p36

Overview: Deletion of material from chromosome 1p (1p36 region) is common in neuroblastoma. It is possible that a tumour supressor gene may be present in this region, though no specific gene has yet been identified.

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  Other Related Resources


Neuroblastoma Chromosome 1p - Recent Publications (NBL1) (Neuroblastoma Online Researcher's Forum)
Neuroblastoma Resources
MYCN gene (2p24.1)
Gain of 17q in Neuroblastoma

  • Medline Search: Neuroblastoma and 1p (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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  • Medline Search: cancer AND gene AND NBL1[TI] (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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  •   del(1p36) in Neuroblastoma

  • Maris JM, et al. Loss of Heterozygosity at 1p36 Independently Predicts for Disease Progression But Not Decreased Overall Survival Probability in Neuroblastoma Patients: A Children's Cancer Group Study. J Clin Oncol 2000 May 9;18(9):1888-1899    Related articles (PubMed)

  • Spieker N, et al. An integrated 5-Mb physical, genetic, and radiation hybrid map of a 1p36.1 region implicated in neuroblastoma pathogenesis. Genes Chromosomes Cancer; 27(2):143-52    Related articles (PubMed)

  • White PS, et al. A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5520-4    Related articles (PubMed)

  • Enomoto H, et al. Identification of human DAN gene, mapping to the putative neuroblastoma tumor suppressor locus. Oncogene. 1994;9(10):2785-91.    Related articles (PubMed)

  • Medline Search: neuroblastoma AND chromosome 1 (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Neuroblastoma Genetics
    Neuroblastoma : Clinical and Epidemiological Information

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