Summary Information - ALK
    Gene Database Entries for ALK
    Other ALK Related Resources
    t(2;5)(p23;q35) NPM1-ALK translocation in NHL
    t(2;5)(p23;q35) NPM1-ALK translocation in Hodgkin's Lymphoma
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ALK; Anaplastic lymphoma kinase (Ki-1)

Location: 2p23

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OMIM
GeneCard (Weizmann Institute)
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Locus Link
UniGene
GDB (search for ALK)
Nomenclature (search for ALK)

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Search Medline for related articles (PubMed)

Medline Search: cancer AND gene AND ALK[TI] (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

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Gascoyne RD, et al. Prognostic significance of anaplastic lymphoma kinase (ALK) protein expression in adults with anaplastic large cell lymphoma. Blood. 1999 Jun 1;93(11):3913-21    Related articles (PubMed)

Trumper L, et al. Detection of the t(2;5)-associated NPM/ALK fusion cDNA in peripheral blood cells of healthy individuals. Br J Haematol 1998; 103(4):1138-44    Related articles (PubMed)

Kadin ME, Morris SW. The t(2;5) in human lymphomas. Leuk Lymphoma 1998; 29(3-4):249-56    Related articles (PubMed)

Medline Search: lymphoma AND npm AND alk (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources
Non-Hodgkin's Lymphoma Genetics
Non-Hodgkin's Lymphoma : Clinical and Epidemiological Information

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Trumper L, et al. NPM/ALK fusion mRNA expression in Hodgkin and Reed-Sternberg cells is rare but does occur: results from single-cell cDNA analysis. Ann Oncol 1997; 8 Suppl 2:83-7    Related articles (PubMed)

Weiss LM, et al. Absence of the t(2;5) in Hodgkin's disease. Blood 1995 May 15;85(10):2845-7    Related articles (PubMed)

Medline Search: Hodgkin's disease AND npm AND alk (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources
Hodgkin's Disease Genetics
Hodgkin's Disease : Clinical and Epidemiological Information

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