Soft Tissue Sarcoma

Overview

Literature Analysis

Mouse over the terms for more detail; many indicate links which you can click for dedicated pages about the topic.

Tag cloud generated 10 March, 2017 using data from PubMed, MeSH and CancerIndex

Mutated Genes and Abnormal Protein Expression (84)

How to use this data tableClicking on the Gene or Topic will take you to a separate more detailed page. Sort this list by clicking on a column heading e.g. 'Gene' or 'Topic'.

GeneLocationAliasesNotesTopicPapers
EWSR1 22q12.2 EWS, EWS-FLI1, bK984G1.4 -EWSR1 and Soft Tissue Sarcoma
521
KIT 4q12 PBT, SCFR, C-Kit, CD117 -KIT and Soft Tissue Sarcoma
192
PTEN 10q23.31 BZS, DEC, CWS1, GLM2, MHAM, TEP1, MMAC1, PTEN1, 10q23del -PTEN and Soft Tissue Sarcoma
83
DDIT3 12q13.1-q13.2 CHOP, CEBPZ, CHOP10, CHOP-10, GADD153 Translocation
-t(12;16)(q13;p11) FUS-DDIT3 in Mixoid Liposarcoma
-DDIT3 and Soft Tissue Cancers
39
AKT1 14q32.32 AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA -AKT1 and Sarcoma
43
FUS 16p11.2 TLS, ALS6, ETM4, FUS1, POMP75, HNRNPP2 Translocation
-t(12;16)(q13;p11) FUS-DDIT3 in Mixoid Liposarcoma
-t(7;16)(q33;p11) FUS-CREB3L2 in Low-grade fibromyxoid sarcoma
39
PAX3 2q35 WS1, WS3, CDHS, HUP2 -PAX3 and Soft Tissue Cancers
36
SLC2A1 1p34.2 PED, DYT9, GLUT, DYT17, DYT18, EIG12, GLUT1, HTLVR, GLUT-1, GLUT1DS -GLUT1 expression in Soft Tissue Sarcoma
34
CD99 Xp22.32 and Yp11.3 MIC2, HBA71, MIC2X, MIC2Y, MSK5X -CD99 and Soft Tissue Cancers
32
JAZF1 7p15.2-p15.1 TIP27, ZNF802 -JAZF1 and Soft Tissue Sarcoma
32
SMARCB1 22q11.23 RDT, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144 -SMARCB1 and Soft Tissue Sarcoma
31
PIK3CA 3q26.3 MCM, CWS5, MCAP, PI3K, CLOVE, MCMTC, p110-alpha -PIK3CA and Soft Tissue Sarcoma
29
ATF1 12q13 TREB36, EWS-ATF1, FUS/ATF-1 -ATF1 and Soft Tissue Cancers
28
MSH2 2p21 FCC1, COCA1, HNPCC, LCFS2, HNPCC1 -MSH2 and Soft Tissue Sarcoma
28
TOP1 20q12-q13.1 TOPI -TOP1 and Soft Tissue Sarcoma
23
MYOG 1q31-q41 MYF4, myf-4, bHLHc3 -MYOG and Soft Tissue Sarcoma
20
MDM4 1q32 HDMX, MDMX, MRP1 -MDM4 and Soft Tissue Sarcoma
17
PAX7 1p36.13 HUP1, RMS2, PAX7B -PAX7 and Soft Tissue Cancers
17
ETV6 12p13 TEL, THC5, TEL/ABL -ETV6 and Soft Tissue Cancers
17
NR4A3 9q22 CHN, TEC, CSMF, NOR1, MINOR -NR4A3 and Soft Tissue Cancers
15
MYB 6q22-q23 efg, Cmyb, c-myb, c-myb_CDS -MYB and Soft Tissue Sarcoma
15
TSPAN31 12q13.3 SAS -TSPAN31 and Soft Tissue Sarcoma
15
MYOD1 11p15.1 PUM, MYF3, MYOD, bHLHc1 -MYOD1 and Soft Tissue Cancers
14
CREB3L2 7q34 BBF2H7 Translocation
-t(7;16)(q33;p11) FUS-CREB3L2 in Low-grade fibromyxoid sarcoma
-CREB3L2 and Soft Tissue Cancers
14
MET 7q31 HGFR, AUTS9, RCCP2, c-Met -C-MET and Soft Tissue Cancers
14
CIC 19q13.2 -CIC and Soft Tissue Cancers
12
BCOR Xp11.4 MAA2, ANOP2, MCOPS2 -BCOR and Soft Tissue Sarcoma
12
PTER 10p12 HPHRP, RPR-1 -PTER and Soft Tissue Cancers
11
CREB1 2q34 CREB -CREB1 and Soft Tissue Cancers
9
ASPSCR1 17q25.3 TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1 Translocation
-der(17)t(X;17)(p11.2;q25) in Alveolar Soft-Part Sarcoma
-ASPSCR1 and Soft Tissue Cancers
8
TCF12 15q21 HEB, CRS3, HTF4, TCF-12, bHLHb20, HsT17266 -TCF12 and Soft Tissue Sarcoma
8
MUC4 3q29 ASGP, MUC-4, HSA276359 -MUC4 and Soft Tissue Cancers
7
HMGA1 6p21 HMG-R, HMGIY, HMGA1A -HMGA1 and Soft Tissue Cancers
7
TFG 3q12.2 TF6, HMSNP, SPG57, TRKT3 -TFG and Soft Tissue Sarcoma
7
CREB3L1 11p11.2 OASIS -CREB3L1 and Soft Tissue Cancers
7
S100A6 1q21 2A9, PRA, 5B10, CABP, CACY -S100A6 and Soft Tissue Sarcoma
7
OSCAR 19q13.42 PIGR3, PIgR-3 -OSCAR and Soft Tissue Sarcoma
7
CD163 12p13.3 M130, MM130 -CD163 and Soft Tissue Sarcoma
6
TGFBR3 1p33-p32 BGCAN, betaglycan -TGFBR3 and Soft Tissue Cancers
6
NCOA2 8q13.3 SRC2, TIF2, GRIP1, KAT13C, NCoA-2, bHLHe75 -NCOA2 and Soft Tissue Cancers
5
CYP3A4 7q21.1 HLP, CP33, CP34, CYP3A, NF-25, CYP3A3, P450C3, CYPIIIA3, CYPIIIA4, P450PCN1 -CYP3A4 and Soft Tissue Sarcoma
5
CTAG1B Xq28 CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 -CTAG1B and Soft Tissue Sarcoma
5
MGEA5 10q24.1-q24.3 OGA, MEA5, NCOAT -MGEA5 and Soft Tissue Cancers
5
CYP3A5 7q21.1 CP35, PCN3, CYPIIIA5, P450PCN3 -CYP3A5 and Soft Tissue Sarcoma
5
MAGEA3 Xq28 HIP8, HYPD, CT1.3, MAGE3, MAGEA6 -MAGEA3 and Soft Tissue Sarcoma
5
YEATS4 12q15 YAF9, GAS41, NUBI-1, 4930573H17Rik, B230215M10Rik -YEATS4 and Soft Tissue Sarcoma
5
DUX4L1 4q35 DUX4, DUX10 -DUX4 and Soft Tissue Cancers
4
TLE1 9q21.32 ESG, ESG1, GRG1 -TLE1 and Soft Tissue Cancers
4
FLT4 5q35.3 PCL, FLT41, LMPH1A, VEGFR3 -FLT4 and Soft Tissue Sarcoma
4
DAPK1 9q21.33 DAPK -DAPK1 and Soft Tissue Cancers
4
GNAS 20q13.3 AHO, GSA, GSP, POH, GPSA, NESP, SCG6, SgVI, GNAS1, C20orf45 -GNAS and Soft Tissue Cancers
4
EZH2 7q35-q36 WVS, ENX1, EZH1, KMT6, WVS2, ENX-1, EZH2b, KMT6A -EZH2 and Soft Tissue Cancers
4
TAF15 17q11.1-q11.2 Npl3, RBP56, TAF2N, TAFII68 -TAF15 and Soft Tissue Cancers
4
DAPK2 15q22.31 DRP1, DRP-1 -DAPK2 and Soft Tissue Cancers
4
GAPDH 12p13 G3PD, GAPD, HEL-S-162eP -GAPDH and Soft Tissue Cancers
3
MED12 Xq13 OKS, FGS1, HOPA, OPA1, OHDOX, ARC240, CAGH45, MED12S, TNRC11, TRAP230 -MED12 and Soft Tissue Cancers
3
PTPRF 1p34 LAR, BNAH2 -PTPRF and Soft Tissue Sarcoma
3
NNAT 20q11.2-q12 Peg5 -NNAT and Soft Tissue Sarcoma
3
PATZ1 22q12.2 ZSG, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, dJ400N23 -PATZ1 and Soft Tissue Sarcoma
3
ICAM1 19p13.3-p13.2 BB2, CD54, P3.58 -ICAM1 and Soft Tissue Cancers
2
TOP2A 17q21-q22 TOP2, TP2A -TOP2A and Soft Tissue Sarcoma
2
LATS1 6q25.1 wts, WARTS -LATS1 and Soft Tissue Sarcoma
2
TPTE 21p11 CT44, PTEN2 -TPTE and Soft Tissue Cancers
2
GSTA1 6p12.1 GST2, GTH1, GSTA1-1 -GSTA1 and Soft Tissue Sarcoma
2
CDKN1B 12p13.1-p12 KIP1, MEN4, CDKN4, MEN1B, P27KIP1 Prognostic
-CDKN1B Expression and Survival in Liposarcoma
2
CD1A 1q23.1 R4, T6, CD1, FCB6, HTA1 -CD1A and Soft Tissue Sarcoma
2
COL1A1 17q21.33 OI1, OI2, OI3, OI4, EDSC -COL1A1 and Soft Tissue Cancers
2
SSTR1 14q13 SS1R, SS1-R, SRIF-2, SS-1-R -SSTR1 and Soft Tissue Cancers
2
TUSC2 3p21.3 PAP, FUS1, PDAP2, C3orf11 -TUSC2 and Soft Tissue Sarcoma
2
MAP2K4 17p12 JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1 -MAP2K4 and Soft Tissue Cancers
2
RANBP2 2q12.3 ANE1, TRP1, TRP2, ADANE, IIAE3, NUP358 -RANBP2 and Soft Tissue Sarcoma
2
PTPRD 9p23-p24.3 HPTP, PTPD, HPTPD, HPTPDELTA, RPTPDELTA -PTPRD and Soft Tissue Sarcoma
2
LDHA 11p15.1 LDHM, GSD11, PIG19, HEL-S-133P -LDHA and Soft Tissue Cancers
1
ACVRL1 12q13.13 HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, TSR-I, ACVRLK1 -ACVRL1 and Soft Tissue Cancers
1
SRSF3 6p21 SFRS3, SRp20 -SRSF3 and Soft Tissue Sarcoma
1
AREG 4q13.3 AR, SDGF, AREGB, CRDGF -AREG and Soft Tissue Cancers
1
ATF6 1q23.3 ATF6A -ATF6 and Soft Tissue Sarcoma
1
PTPRC 1q31-q32 LCA, LY5, B220, CD45, L-CA, T200, CD45R, GP180 -PTPRC and Soft Tissue Sarcoma
1
ANO1 11q13.3 DOG1, TAOS2, ORAOV2, TMEM16A -ANO1 and Soft Tissue Cancers
1
SSX1 Xp11.23 SSRC, CT5.1 Translocation
-t(X;18)(p11.2;q11.2) SS18-SSX1 in Synovial Sarcoma
TFE3 Xp11.22 TFEA, RCCP2, RCCX1, bHLHe33 Translocation
-der(17)t(X;17)(p11.2;q25) in Alveolar Soft-Part Sarcoma
SSX2 Xp11.22 SSX, HD21, CT5.2, CT5.2A, HOM-MEL-40 Translocation
-t(X;18)(p11.2;q11.2) SS18-SSX2 in Synovial Sarcoma
SSX4 Xp11.23 CT5.4 Translocation
-t(X;18)(p11.2;q11.2) SS18-SSX4 in Synovial Sarcoma
SS18 18q11.2 SYT, SSXT Translocation
-t(X;18)(p11.2;q11.2) SS18-SSX1 in Synovial Sarcoma
-t(X;18)(p11.2;q11.2) SS18-SSX2 in Synovial Sarcoma
-t(X;18)(p11.2;q11.2) SS18-SSX4 in Synovial Sarcoma

Note: list is not exhaustive. Number of papers are based on searches of PubMed (click on topic title for arbitrary criteria used).

Disclaimer: This site is for educational purposes only; it can not be used in diagnosis or treatment.

Cite this page: Cotterill SJ. Soft Tissue Sarcoma, Cancer Genetics Web: http://www.cancer-genetics.org/X2003.htm Accessed:

Creative Commons License
This page in Cancer Genetics Web by Simon Cotterill is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Note: content of abstracts copyright of respective publishers - seek permission where appropriate.

 [Home]    Page last revised: 10 March, 2017     Cancer Genetics Web, Established 1999