Summary Information
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Location: 4p11-q22
Aliases: CD117, SCFR
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Gene Database Entries for KIT
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OMIM
GeneCard (Weizmann Institute)
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Human Gene Mutation Database (Cardiff, UK)
Tumor Gene Database
Swiss-Prot
PROW protein review
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for KIT)
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Other Related Resources
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Medline Search: KIT (PubMed)
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- Medline Search: cancer AND gene AND (KIT[TI] OR CD117[TI] OR SCFR[TI]) (PubMed)
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KIT and Gastrointestinal Stromal Tumours
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Heinrich MC, et al. Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations. Hum Pathol 2002;33(5):484-95 Related articles (PubMed)
Hirota S, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998 Jan 23;279(5350):577-80 Related articles (PubMed)
Moskaluk CA, et al. Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors. Oncogene 1999 Mar 11;18(10):1897-902 Related articles (PubMed)
Lasota J, et al. Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas. Am J Pathol 1999;154(1):53-60 Related articles (PubMed)
Medline Search: gastrointestinal stromal tumor AND (kit OR c-kit) (PubMed)
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Adult Soft Tissue Sarcoma Genetics
Adult Soft Tissue Sarcoma : Clinical and Epidemiological Information
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KIT and Mast Cell Leukaemia
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Tsujimura T Role of c-kit receptor tyrosine kinase in the development, survival and neoplastic transformation of mast cells. [Review] Pathol Int 1996;46(12):933-8 Related articles (PubMed)
Medline Search: mast cell leukemia AND (kit OR c-kit) (PubMed)
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KIT Expression in Acute Myeloblastic Leukaemia
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Schwartz S, et al. Expression of the C-kit receptor (CD117) is a feature of almost all subtypes of de novo acute myeloblastic leukemia (AML), including cytogenetically good-risk AML, and lacks prognostic significance. Leuk Lymphoma 1999;34(1-2):85-94 Related articles (PubMed)
Medline Search: acute myeloblastic leukemia AND (kit OR c-kit) (PubMed)
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Acute Myeloid Leukaemia Genetics
Acute Myeloid Leukaemia : Clinical and Epidemiological Information
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KIT and Germ Cell Tumours
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Tian Q, et al. Activating c-kit gene mutations in human germ cell tumors. Am J Pathol 1999;154(6):1643-7 Related articles (PubMed)
Medline Search: germ cell tumor AND (kit OR c-kit) (PubMed)
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[Home] This page created: 09/10/1999 Last revised: 29/04/2003 © Copyright 1999-
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