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KIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (4p11-q22)
KIT Menu

    Summary Information - KIT
    Gene Database Entries for KIT
    Other KIT Related Resources
    KIT and Gastrointestinal Stromal Tumours
    KIT and Mast Cell Leukaemia
    KIT Expression in Acute Myeloblastic Leukaemia
    KIT and Germ Cell Tumours
    Feedback / suggest a new topic for KIT


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  Summary Information

KIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Location: 4p11-q22

Aliases: CD117, SCFR

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  Gene Database Entries for KIT

OMIM
GeneCard (Weizmann Institute)
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Human Gene Mutation Database (Cardiff, UK)
Tumor Gene Database
Swiss-Prot
PROW protein review
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for KIT)

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  Other Related Resources

  • Medline Search: KIT (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
    Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (KIT[TI] OR CD117[TI] OR SCFR[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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  •   KIT and Gastrointestinal Stromal Tumours

  • Heinrich MC, et al. Biology and genetic aspects of gastrointestinal stromal tumors: KIT activation and cytogenetic alterations. Hum Pathol 2002;33(5):484-95    Related articles (PubMed)

  • Hirota S, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998 Jan 23;279(5350):577-80    Related articles (PubMed)

  • Moskaluk CA, et al. Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors. Oncogene 1999 Mar 11;18(10):1897-902    Related articles (PubMed)

  • Lasota J, et al. Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas. Am J Pathol 1999;154(1):53-60    Related articles (PubMed)

  • Medline Search: gastrointestinal stromal tumor AND (kit OR c-kit) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Adult Soft Tissue Sarcoma Genetics
    Adult Soft Tissue Sarcoma : Clinical and Epidemiological Information

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  •   KIT and Mast Cell Leukaemia

  • Tsujimura T Role of c-kit receptor tyrosine kinase in the development, survival and neoplastic transformation of mast cells. [Review] Pathol Int 1996;46(12):933-8    Related articles (PubMed)

  • Medline Search: mast cell leukemia AND (kit OR c-kit) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

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  •   KIT Expression in Acute Myeloblastic Leukaemia

  • Schwartz S, et al. Expression of the C-kit receptor (CD117) is a feature of almost all subtypes of de novo acute myeloblastic leukemia (AML), including cytogenetically good-risk AML, and lacks prognostic significance. Leuk Lymphoma 1999;34(1-2):85-94    Related articles (PubMed)

  • Medline Search: acute myeloblastic leukemia AND (kit OR c-kit) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Acute Myeloid Leukaemia Genetics
    Acute Myeloid Leukaemia : Clinical and Epidemiological Information

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  •   KIT and Germ Cell Tumours

  • Tian Q, et al. Activating c-kit gene mutations in human germ cell tumors. Am J Pathol 1999;154(6):1643-7    Related articles (PubMed)

  • Medline Search: germ cell tumor AND (kit OR c-kit) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources

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