 Mutated Genes and Abnormal Protein Expression
|
| Gene | Location | Topics
|
| PTPRC (
CD45
, LCA
, GP180
)
| 1q31-q32
|
-CD45 and Acute Myeloid Leukaemia
-CD45 Targeted Antibody Chemotherapy in AML
|
| MLF1 | 3q25.1
|
|
| KIT (
CD117
, SCFR
, cKit
)
| 4p11-q22
|
-KIT Expression in Acute Myeloblastic Leukaemia
|
| DEK (
D6S231E
)
| 6p23
|
|
| HOXA9 (
HOX1
, HOX1G
)
| 7p15-p14.2
|
|
| CBFA2T1 (
ETO
, MTG8
, CDR
)
| 8q22
|
|
| NUP214 (
CAN
, D9S46E
)
| 9q34.1
|
-t(6;9)(p23;q34) in Acute Myeloid Leukaemia
-CAN-SET Translocation in Acute
|
| NUP98 | 11p15
|
-t(7;11)(p15;p15) in Acute Myelogenous Leukaemia
|
| MLL (
ALL1
, HRX
)
| 11q23
|
-t(9;11) in Acute Myeloid Leukaemia
|
| ETV6 (
TEL
)
| 12p13
|
-t(1;12)(q25;p13) in Acute Myeloid Leukaemia
|
| MRP (
MRP1
, ABCC1
)
| 16p13.1
|
-MRP1 and Acute Myeloid Leukaemia
-MRP1 Deletion in Acute Myeloid Leukaemia with INV(16)
|
| CBFB (
PEBP2b
)
| 16q22.1
|
-t(16;16)(p13q22) CBFB-MYH11 Translocation in AML
|
| HIC1 | 17p13.3-17p13.3
|
-HIC1 and Acute Myeloid Leukemia
|
| BCL2 | 18q21.3
|
-BCL2 and Acute Myelogenous Leukaemia
|
| AXL (
UFO
)
| 19q13.1
|
-AXL Expression and Prognosis in Acute Myeloid Leukemia
|
| BAX | 19q13.3-q13.4
|
-BAX and Acute Myeloid Leukemia
|
| CD33 (
GP67
)
| 19q13.3-q13.4
|
-CD33 and Acute Myloid Leukaemia
-CD33 Targeted Antibody Chemotherapy in AML
|
| ERG | 21q22.3
|
-t(8; 21) Translocation in Acute Myelogenous Leukemia
-t(16;21)(p11;q22) in Acute Myelogenous Leukemia
|
| CBFA2 (
AML1
, PEBP2A2
, RUNX1
)
| 21q22.3
|
-t(8;21)(q22;q22) in Acute Myeloid Leukemia
|
|
Acute Myeloid Leukaemia: Clinical and Epidemiological Resources