Summary Information - PTPRC
    Gene Database Entries for PTPRC
    Other PTPRC Related Resources
    CD45 and Acute Myeloid Leukaemia
       - CD45 Targeted Antibody Chemotherapy in AML
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PTPRC;

Location: 1q31-q32

Aliases: CD45, LCA

A cell-surface antigen expressed by all circulating leukocytes and lymphocytes. A leukaemia marker and target for therap

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OMIM
GeneCard (Weizmann Institute)
Genbank
Swiss-Prot
PROW protein review
Locus Link (search for PTPRC)
UniGene
GenAtlas
GDB
Nomenclature (search for PTPRC)

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Search Medline for related articles (PubMed)

Medline Search: cancer AND gene AND (PTPRC[TI] OR CD45[TI] OR LCA[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

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Miyachi H, et al. Altered expression of CD45 isoforms in differentiation of acute myeloid leukemia. Am J Hematol 1999; 62(3):159-64    Related articles (PubMed)

Medline Search: acute myloid leukemia AND cd45 (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources
Acute Myeloid Leukaemia Genetics
Acute Myeloid Leukaemia : Clinical and Epidemiological Information

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Appelbaum FR. Antibody-targeted therapy for myeloid leukemia. [Review] Semin Hematol. 1999;36(4 Suppl 6):2-8.    Related articles (PubMed)

Matthews DC, et al. Phase I study of (131)I-anti-CD45 antibody plus cyclophosphamide and total body irradiation for advanced acute leukemia and myelodysplastic syndrome. Blood. 1999; 94(4):1237-47    Related articles (PubMed)

Matthews DC, et al. Development of a marrow transplant regimen for acute leukemia using targeted hematopoietic irradiation delivered by 131I-labeled anti-CD45 antibody, combined with cyclophosphamide and total body irradiation. Blood. 1995; 85(4):1122-31    Related articles (PubMed)

Medline Search: acute myloid leukemia AND cd45 (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources

Cancer Immunology and Immunotherapy
Acute Myeloid Leukaemia Genetics
Acute Myeloid Leukaemia : Clinical and Epidemiological Information

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