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Soft tissue sarcomas are malignant tumours that may arise in any of the mesodermal tissues (muscles, tendons, vessels that carry blood or lymph, joints, and fat). Sarcomas are a diverse range of tumours, they are named after the type of soft tissue cell
they arise from. Types of soft tissue sarcomas include;
alveolar soft-part sarcoma, angiosarcoma, fibrosarcoma, leiomyosarcoma, liposarcoma, malignant fibrous histiocytoma, hemangiopericytoma, mesenchymoma, schwannoma, peripheral neuroectodermal tumours, rhabdomyosarcoma, synovial sarcoma, and other
types. In terms of treatment these different sub-types are usually treated in the same way using a uniform soft tissue protocol.
- General Resources
- Childhood Soft Tissue Sarcoma
- Adult Soft Tissue Sarcoma
- Kaposi's Sarcoma
General Resources (11 links)
- SARCOMA-MED (ACOR) a list for medical queries relating to sarcomas - not a general discussion list. Specialist sarcoma physicians have volunteered to answer medical queries posted to the list.
- Sarcoma.Net An educational site for sarcoma patients including sarcoma facts, information about clinical trials and links. The site is by George Demetri, MD a sarcoma specialist at the Dana-Farber Cancer Institute.
- SarcomaSurvivors A site for survivors or others touched by sarcoma cancer to get together and provide support for each other. The Web site has details of membership, a chat room, message board, group-Email, survivors photos and links. Warning: public Email list.
- Soft Tissue Sarcomas (CancerHelp UK) Information about the cancer, diagnosis, treatment and living with the disease.
- Soft-Tissue Sarcoma Overview (Memorial Sloan-Kettering Cancer Center)
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- CancerLit: Sarcoma (National Cancer Institute) On-line abstracts for health professionals. Sorted by month and year for soft tissue sarcoma / rhabdomyosarcoma
- Connective Tissue Oncology Society An international group of physicians and scientists founded in 1995 to advance the care of patients and to advance basic and clinical research into connective tissue tumors. The site includes details of the society, membership, meetings, registry etc
- Sarcoma (Journal) a peer reviewed international journal publishing papers covering all aspects of connective tissue oncology research. Table of Contents Email service.
- Soft Tissue Sarcoma of the Extremities..Clinicopathologic and MRI Features (MD Anderson Cancer Center)
Childhood Soft Tissue Sarcoma (14 links)
Childhood soft tissue sarcomas account for approximately 10% of all childhood cancers. About half of all childhood soft tissue sarcomas are rhabdomyosarcoma, which arises from skeletal muscle, these are most common between the ages of 2 and 6. The other
soft tissue sarcomas of childhood include a wide range of different histologies including fibrosarcoma, leiomyosarcoma, liposarcoma, schwannoma, soft tissue Ewing's / peripheral neuroectodermal tumours, synovial sarcoma and many other types. These
non-rhabdo sarcomas are more common in adults, but these tumours usually behave quite differently in children compared to the same tumours in adults.
- Patient's information for Childhood Soft Tissue (Non-Rhabdomyosarcoma) (CancerNet) Information about the disease, staging, and treatment overviews. It is reviewed each month by a panel of medical experts.
- Patient's information for Childhood Rhabdomyosarcoma (CancerNet) Information about the disease, staging, and treatment overviews. It is reviewed each month by a panel of medical experts.
- Alistair's Home Page Alistair was diagnosed with Rhabdomyosarcoma, age 11. This page tells his story with information about the disease and treatment and how Alistair has done since finishing therapy in February 1996. Great pictures and art work.
- Cassandra's Home Page Home page of a child diagnosed with Rhabdomyosarcoma
- Children's Oncology Group Soft Tissue Sarcoma Committee (COG STS) (USA) COG STS is funded by the National Cancer Institute and conducts research into rhabdomyosarcoma. The web site includes material for public and health professionals including details about the disease and information about clinical trials.
- General information for rhabdomyosarcoma (St Jude's Children's Research Hospital)
- Joshua Gilbert Rhabdomyosarcoma Appeal (UK) a charity founded in the memory of Joshua who died from Rhabdomyosarcoma in 1994. The appeal was established to raise money for research into this disease. The site includes details of the charity, research reports, events etc.
- Paediatric - Soft Tissue Sarcoma (Royal Marsden Hospital, UK) An on-line booklet.
- Pediatric Oncology Resource Center: Rhabdomyosarcoma (USA) This page contains information and links on various aspects of childhood leukemia. It is part of the Pediatric Oncology Resource Center, a site produced by parents of children with cancer, hosted by Association of Cancer Online Resources.
- Rhabdomyosarcoma (UK) a factsheet produced by the United Kingdom Children's Cancer Study Group and CancerBacup linked to the UKCCSG booklet "A Parent's Guide to Children's Cancers".
- Stories and Faces: Rhabdomyosarcoma (Pediatric Oncology Resource Center) List of home pages of children affected by rhabdomyosarcoma
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- Physician's PDQ statement for Childhood Rhabdomyosarcoma (CancerNet) A referenced overview of the disease, cellular classification, staging, and current treatment overviews. It is reviewed each month by experts at the NCI.
- Physician's PDQ statement for Childhood Soft Tissue(Non-Rhabdomyosarcoma) (CancerNet) A referenced overview of the disease, cellular classification, staging, and current treatment overviews. It is reviewed each month by experts at the NCI.
- Childhood Soft Tissue Sarcomas (USA) Part of a SEER report on cancer incidence and survival among children and adolescents; 1975-1995. PDF format.
See also Childhood Cancer Resources
Adult Soft Tissue Sarcoma (15 links)
Soft tissue sarcomas are malignant tumours that may arise in any of the mesodermal tissues (muscles, tendons, vessels that carry blood or lymph, joints, and fat). The peak age
incidence is around 50 years. Sarcomas are a diverse range of tumours, they are named after the type of soft tissue cell they arise from. Types of soft tissue sarcomas include;
alveolar soft-part sarcoma, angiosarcoma, fibrosarcoma, leiomyosarcoma, liposarcoma, malignant fibrous histiocytoma, hemangiopericytoma, mesenchymoma, schwannoma, peripheral neuroectodermal tumours, rhabdomyosarcoma, synovial sarcoma, and other
types.
Kaposi's sarcoma is a type of cancer where malignant cells are found in the tissues under
the skin, lining of the mouth, nose, and anus. Symptoms may include red or purple patches
(lesions) on the skin and other parts of the body. Many (though not all) Kaposi's sarcomas are AIDS related.
- Patient's information for Adult Soft Tissue Sarcoma (CancerNet) Information about the disease, staging, and treatment overviews. It is reviewed each month by a panel of medical experts.
- Adjuvant chemotherapy for localised resectable soft tissue sarcoma in adults (Cochrane Collaboration) Abstract of a systematic review.
- L-M-SARCOMA - Leiomyosarcoma Electronic Support Group Email discussion list
- L-SARCOMA - Liposarcoma Information and Support Group (ACOR) Email list
- Questions and Answers: Muscle, nerve and connective tissue cancers From the CancerHelp Web site produced by Cancer Research UK.
- SARCOMA - Sarcoma Electronic Support Group Email discussion list
- Soft Tissue Sarcoma People Organization A non-profit organization to support sarcoma cancer patients, survivors, families and friends in Europe founded in 1997 by the brother of a synovial sarcoma patient. The site includes information about sarcomas, detailed links and other resources.
- Understanding Soft Tissue Sarcomas (BACUP, UK) An on-line booklet
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- Physician's PDQ statement for Adult Soft Tissue Sarcoma (CancerNet) A referenced overview of the disease, cellular classification, staging, and current treatment overviews. It is reviewed each month by experts at the NCI.
- Case study: A 42 year old man with trigeminofacial malignant epithelioid schwannoma (Department of Pathology, University of Pittsburgh)
- Case study: A sixty-seven year old female with cutaneous leiomyosarcoma (Department of Pathology, University of Pittsburgh)
- Case study: A twenty-five year old female with leiomyosarcoma (Department of Pathology, University of Pittsburgh)
- Physician's information on Soft Tissue Sarcoma (START, European School of Oncology) Referenced statement including sections on epidemiology, pathology, diagnosis, staging, treatment and follow-up produced by an editorial board of top European oncologists. [Go to Chapters]
Kaposi's Sarcoma (9 links)
See also AIDS Related Cancers
See also t(11;22) translocation in DSRCT
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