 Mutated Genes and Abnormal Protein Expression
|
| Gene | Location | Topics
|
| S100A4 (
MTS1
, P9KA
, metastasin
)
| 1q21
|
-S100A4 and Osteosarcoma
|
| MYCN (
NMYC
, N-MYC
)
| 2p24.1
|
-MYCN Amplification in Osteosarcoma
|
| NRG1 (
HRGA
, GGF2
, HGL
)
| 8p22-p11
|
-NGR1 and Medulloblastoma
|
| EXT1 | 8q24.11-q24.13
|
|
| MYC (
CMYC
, C-MYC
)
| 8q24.12-q24.13
|
-MYC and Osteosarcoma
|
| RECQL4 (
RTS
)
| 8q24.3
|
-Rothmund-Thomson Syndrome and Osteosarcoma
|
| CDKN2A (
P16
, INK4A
, MTS1
)
| 9p21
|
-CDKN2A and Osteosarcoma
|
| CD44 (
MDU3
, HA
, MDU2
)
| 11pter-p13
|
-CD44 and Osteosarcoma
|
| PRIM1 | 12q13
|
-PRIM1 Amplification in Osteosarcoma
|
| MDM2 | 12q13-q14
|
-MDM2 and Osteosarcoma
|
| SAS | 12q13-q14
|
-SAS and Osteosarcoma
|
| CDK4 (
PSK-J3
)
| 12q14
|
-CDK4 Amplification in Osteosarcoma
|
| RB1 (
Rb
)
| 13q14.2
|
-RB1 and Osteosarcoma
|
| MMP2 (
CLG4A
, CLG4
, GELA
)
| 16q13
|
-MMP2 and Osteosarcoma
|
| TP53 (
p53
, P53
)
| 17p13.1
|
-TP53 and Osteosarcoma
|
| ERBB2 (
HER2
, NEU
)
| 17q11.2-q12
|
-ERBB2 and Osteosarcoma
|
| LOH18CR1 (
OSTS
)
| 18q21-q22
|
-LOH18CR1 and Osteosarcoma in Paget's Disease
|
| CHEK2 (
CHK2
, RAD53
, CDS1
)
| 22q12.1
|
-CHEK2 mutations in Osteosarcoma
|
|
Osteosarcoma: Clinical and Epidemiological Resources