 Summary Information
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Location: 16q13
Aliases: CLG4A, CLG4
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| Gene Database Entries for MMP2
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OMIM
GeneCard (Weizmann Institute)
Genbank
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for MMP2)
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| Other Related Resources
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- Search Medline for related articles (PubMed)
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- Medline Search: cancer AND gene AND (MMP2[TI] OR CLG4A[TI] OR CLG4[TI]) (PubMed)
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| MMP2 and Gastric Carcinomas
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Sier CF, et al. Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinoma. Br J Cancer 1996; 74(3):413-7 Related articles (PubMed)
Medline Search: gastric carcinoma AND (mmp2 OR gelatinase A) (PubMed)
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| MMP2 and Liver Cancer
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Musso O, et al. In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis. J Hepatol. 1997;26(3):593-605. Related articles (PubMed)
Theret N, et al. Overexpression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 in liver from patients with gastrointestinal adenocarcinoma and no detectable metastasis Int J Cancer. 1997 Aug 22;74(4):426-32 Related articles (PubMed)
Medline Search: liver cancer AND (mmp2 OR gelatinase A) (PubMed)
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 Hepatocelular Carcinoma Genetics
Hepatocelular Carcinoma : Clinical and Epidemiological Information
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| MMP2 and Malignant Melanoma
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Walker RA, Woolley DE Immunolocalisation studies of matrix metalloproteinases-1, -2 and -3 in human melanoma. Virchows Arch 1999;435(6):574-9 Related articles (PubMed)
Hofmann UB, et al. Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression. Br J Cancer. 1999;81(5):774-82 Related articles (PubMed)
Kurschat P, et al. Tissue inhibitor of matrix metalloproteinase-2 regulates matrix metalloproteinase-2 activation by modulation of membrane-type 1 matrix metalloproteinase activity in high and low invasive melanoma cell lines. J Biol Chem. 1999 Jul 23;274(30):21056-62. Related articles (PubMed)
Vaisanen A, et al. Matrix metalloproteinase-2 (72 kD type IV collagenase) expression occurs in the early stage of human melanocytic tumour progression and may have prognostic value. J Pathol. 1996; 180(3):283-9 Related articles (PubMed)
Medline Search: malignant melanoma AND (mmp2 OR gelatinase A) (PubMed)
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Melanoma Genetics
Melanoma : Clinical and Epidemiological Information
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| MMP2 and Colorectal Cancer
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Zeng ZS, et al. Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis Carcinogenesis. 1999;20(5):749-55 Related articles (PubMed)
Medline Search: colorectal cancer AND (mmp2 OR gelatinase A) (PubMed)
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ColoRectal Cancers Genetics
ColoRectal Cancers : Clinical and Epidemiological Information
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| MMP2 and Oral Cancers
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Ikebe T, et al. Gelatinolytic activity of matrix metalloproteinase in tumor tissues correlates with the invasiveness of oral cancer. Clin Exp Metastasis 1999;17(4):315-23 Related articles (PubMed)
Medline Search: oral cancer AND (mmp2 OR gelatinase A) (PubMed)
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Oral cavity, Lip, Salivary gland Ca. Genetics
Oral cavity, Lip, Salivary gland Ca.: Clinical and Epidemiological Information
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| MMP2 and CNS Tumours
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Forsyth PA, et al. Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas. Br J Cancer. 1999;79(11-12):1828-35. Related articles (PubMed)
Friedberg MH, et al. Specific matrix metalloproteinase profiles in the cerebrospinal fluid correlated with the presence of malignant astrocytomas, brain metastases, and carcinomatous meningitis. Cancer 1998 Mar 1;82(5):923-30 Related articles (PubMed)
Medline Search: brain tumor AND (mmp2 OR gelatinase A) (PubMed)
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Brain and CNS Tumours : Clinical and Epidemiological Information
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| MMP2 and Chondrosarcoma
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Sakamoto A, et al. Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma. J Cancer Res Clin Oncol 1999;125(10):541-8 Related articles (PubMed)
Medline Search: chondrosarcoma AND (mmp2 OR gelatinase A) (PubMed)
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Chondrosarcoma Genetics
Chondrosarcoma : Clinical and Epidemiological Information
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| MMP2 and Osteosarcoma
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Bjornland K, et al. S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme. Cancer Res 1999 Sep 15;59(18):4702-8 Related articles (PubMed)
Medline Search: osteosarcoma AND (mmp2 OR gelatinase A) (PubMed)
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Osteosarcoma Genetics
Osteosarcoma : Clinical and Epidemiological Information
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| MMP2 and Breast Cancer
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Tetu B, et al. Prognostic significance of stromelysin 3, gelatinase A, and urokinase expression in breast cancer. Hum Pathol 1998 Sep;29(9):979-85 Related articles (PubMed)
Medline Search: breast cancer AND (mmp2 OR gelatinase A) (PubMed)
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Breast Cancer Genetics
Breast Cancer : Clinical and Epidemiological Information
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[Home] This page created: 10/03/2000 Last revised: 29/04/2003 © Copyright 1999-
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