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  Hepatocelular Carcinoma

Mutated Genes and Abnormal Protein Expression (21)
Microbiology of Liver Cancer
Familial Clustering of Hepatocellular Carcinoma
Childhood Hepatocellular Carcinoma and Gardner Syndrome
CGH Studies of HCC
Hepatocelular Carcinoma: Clinical and Epidemiological Resources
  Mutated Genes and Abnormal Protein Expression
GeneLocationTopics
BCL10 ( CLAP , CIPER ) 1p22 -BCL10 Point Mutations in Hepatocellular Carcinoma
PAP2p12 -PAP Expression in Hepatocarcinoma
LCO2q14-q21 -LCO and Liver Cancer
CTNNB1 ( CTNNB ) 3p22-p21.3 -CTNNB1 and Hepatocellular Carcinoma
SPARC ( ON , OSN , BM-40 ) 5q31.3-q32 -SPARC Over-expression in Hepatocellular Carcinoma
HFE ( HLA-H ) 6p21.3 -HFE Mutations in Hepatocellular Carcinoma
MET ( HGFR , c-met ) 7q31 -MET and Hepatocellular Carcinoma
-MET and Childhood Hepatocellular Carcinoma
DLC18p22-p21.3 -DLC1 and Hepatocellular Carcinoma
MGMT10q26 -MGMT and Hepatocellular Carcinma
KAI1 ( CD82 , R2 , ST6 ) 11p11.2 -KAI1 and Hepatocellular Carcinoma
CDKN1C ( KIP2 , P57 ) 11p15.5 -CDKN1C Expression in Hepatocarcinoma
IGF211p15.5 -IGF2 Expression in Hepatocarcinoma
SLC22A1L ( BWSCR1A , ORCTL2 , IMPT1 ) 11p15.5 -SLC22A1L Expression in Hepatocarcinoma
CD44 ( MDU3 , HA , MDU2 ) 11pter-p13 -CD99 Expression in Hepatocellular Carcinoma
MMP12 ( HME ) 11q22.2-q22.3 -MMP12 Expression in Hepatocellular Carcinoma
IGF112q22-q24.1 -IGF1 Expression in Hepatocellular Carcinoma
AXIN116p13.3 -AXIN2 and Hepatocellular Carcinoma
MMP2 ( CLG4A , CLG4 , GELA ) 16q13 -MMP2 and Liver Cancer
TP53 ( p53 , P53 ) 17p13.1 -TP53 and Liver Cancer
TIMP217q25 -TIMP2 and Liver Cancer
BIRC5 ( survivin , SVV , API4 ) 17q25(?) -Survivin Expression in Hepatocellular Carcinoma

 

  Microbiology of Liver Cancer

  • Imazeki F, Saisho H Molecular mechanism of hepatocarcinogenesis. [Review] Gan To Kagaku Ryoho 1999;26(14):2154-61    Related articles (PubMed)

  • Hui AM, et al. Cell cycle regulators and human hepatocarcinogenesis. Hepatogastroenterology 1998 Sep-Oct;45(23):1635-42    Related articles (PubMed)

  • Ozturk M Genetic aspects of hepatocellular carcinogenesis. Semin Liver Dis 1999;19(3):235-42    Related articles (PubMed)

  • Marion MJ, Boivin-Angele S Vinyl chloride-specific mutations in humans and animals. [Review] IARC Sci Publ 1999;(150):315-24    Related articles (PubMed)

  • Medline Search: liver cancer AND genetics (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Hepatocelular Carcinoma Genetics
    Hepatocelular Carcinoma : Clinical and Epidemiological Information

     

  •   Familial Clustering of Hepatocellular Carcinoma

  • Yu MW, et al. Familial Risk of Hepatocellular Carcinoma Among Chronic Hepatitis B Carriers and Their Relatives. J Natl Cancer Inst 2000 Jul 19;92(14):1159-1164    Related articles (PubMed)

  • Yu MW, et al. A p53 genetic polymorphism as a modulator of hepatocellular carcinoma risk in relation to chronic liver disease, familial tendency, and cigarette smoking in hepatitis B carriers. Hepatology 1999 Mar;29(3):697-702    Related articles (PubMed)

    Hepatocelular Carcinoma Genetics
    Hepatocelular Carcinoma : Clinical and Epidemiological Information

     

  •   Childhood Hepatocellular Carcinoma and Gardner Syndrome

  • Gruner BA, et al. Hepatocellular carcinoma in children associated with Gardner syndrome or familial adenomatous polyposis. J Pediatr Hematol Oncol 1998 May-Jun;20(3):274-8    Related articles (PubMed)

  • Medline Search: Gardner syndrome AND Hepatocellular carcinoma (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Hepatocelular Carcinoma Genetics
    Hepatocelular Carcinoma : Clinical and Epidemiological Information

     

  •   CGH Studies of HCC

  • Chen YJ, et al. Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma. Gastroenterology 2000 Aug;119(2):431-40    Related articles (PubMed)

  • Sakakura C, et al. Chromosomal aberrations in human hepatocellular carcinomas associated with hepatitis C virus infection detected by comparative genomic hybridization. Br J Cancer 1999 Aug;80(12):2034-9    Related articles (PubMed)

  • Wong N, et al. Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis: relationship to disease stage, tumor size, and cirrhosis. Am J Pathol 1999 Jan;154(1):37-43    Related articles (PubMed)

  • Zimmermann U, et al. Chromosomal aberrations in hepatocellular carcinomas: relationship with pathological features. Hepatology 1997 Dec;26(6):1492-8    Related articles (PubMed)

  • Marchio A, et al. Recurrent chromosomal abnormalities in hepatocellular carcinoma detected by comparative genomic hybridization. Genes Chromosomes Cancer 1997 Jan;18(1):59-65    Related articles (PubMed)

    Hepatocelular Carcinoma Genetics
    Hepatocelular Carcinoma : Clinical and Epidemiological Information

     

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