ARHC - RAS homolog gene family, member C - aka: RhoC

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ARHC; RAS homolog gene family, member C (1p21-p13)
ARHC Menu Summary Information - ARHC Gene Database Entries for ARHC Other ARHC Related Resources RhoC and Metastases in Melanoma RhoC Overexpression in Inflammatory Breast Cancer RhoC Expression and Prognosis in Ductal Pancreatic Cancer Feedback / suggest a new topic for ARHC
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Summary Information
ARHC; RAS homolog gene family, member C Location: 1p21-p13 Alias: RhoC Overview: RhoC over-expression has been reported in ductal pancreatic adenosarcoma (Suwa, 1998) and in inflammatory breast cancers (van Golen, 1999). RhoC is also implicated in the spread of metastastic disease (Clarke, 2000). Return to ARHC Contents
Gene Database Entries for ARHC
OMIM GeneCard (Weizmann Institute) Swiss-Prot Locus Link UniGene GenAtlas GDB Nomenclature (search for ARHC) Return to ARHC Contents
Other Related Resources
Search Medline for related articles (PubMed) *Medline Search:* cancer AND gene AND (ARHC[TI] OR RhoC[TI]) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to ARHC Contents
RhoC and Metastases in Melanoma
Clarke EA et al. Genomic analysis of metastasis reveals an essential role for RhoC Nature 2000; 406, 532 - 535 *Medline Search:* melanoma AND (rhoc OR arhc) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources Melanoma Genetics Melanoma : Clinical and Epidemiological Information Return to ARHC Contents
RhoC Overexpression in Inflammatory Breast Cancer
In an in-situ hybridization study RohC was more frequently over-expressed in inflammatory breast cancers compared with non-inflammatory breast cancers (van Golen,1999). van Golen et al. A Novel Putative Low-Affinity Insulin-like Growth Factor-binding Protein, LIBC (Lost in Inflammatory Breast Cancer), and RhoC GTPase Correlate with the Inflammatory Breast Cancer Phenotype. Clinical Cancer Research 1999; 5: 2511-19 Related articles (PubMed) *Medline Search:* breast cancer AND (rhoc OR arhc) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources Breast Cancer Genetics Breast Cancer : Clinical and Epidemiological Information Return to ARHC Contents
RhoC Expression and Prognosis in Ductal Pancreatic Cancer
Suwa H et al. Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas. Br J Cancer 1998;77:147-52 Related articles (PubMed) *Medline Search:* pancreatic cancer AND (rhoc OR arhc) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources Pancreatic Cancer Genetics Pancreatic Cancer : Clinical and Epidemiological Information Return to ARHC Contents
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ARHC; RAS homolog gene family, member C