Summary Information - CYP2B Gene Database Entries for CYP2B Other CYP2B Related Resources Cytochromes and Cyclophosphamide / Ifosfamide Activation CYP2B and Gene Therapy (Experimental) Feedback / suggest a new topic for CYP2B
CYP2B; Cytochrome P450, subfamily IIB (phenobarbital-inducible) Location: 19q13.1-q13.2 Alias: CYP2B1 Return to CYP2B Contents
Location: 19q13.1-q13.2 Alias: CYP2B1
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OMIM GeneCard (Weizmann Institute) Locus Link GDB Nomenclature (search for CYP2B) Return to CYP2B Contents
Search Medline for related articles (PubMed) Medline Search: cancer AND gene AND (CYP2B[TI] OR CYP2B1[TI]) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to CYP2B Contents
Chang TK, et al. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Res 1993; 53(23):5629-37 Related articles (PubMed) Lohr M, et al. Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting pancreatic carcinoma: a phase I/II study. J Mol Med 1999; 77(4):393-8 Related articles Muller P, et al. Injection of encapsulated cells producing an ifosfamide-activating cytochrome P450 for targeted chemotherapy to pancreatic tumors. Ann N Y Acad Sci 1999; 880:337-51 Related articles (PubMed) Aghi M, et al. Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies. Cancer Res. 1999; 59(16):3861-5 Related articles (PubMed) Medline Search: (cytochromes OR P450) AND (ifosfamide OR cyclophosphamide) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources Chemotherapy Resources Return to CYP2B Contents
Lohr M, et al. Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting pancreatic carcinoma: a phase I/II study. J Mol Med 1999; 77(4):393-8 Related articles Muller P, et al. Injection of encapsulated cells producing an ifosfamide-activating cytochrome P450 for targeted chemotherapy to pancreatic tumors. Ann N Y Acad Sci 1999; 880:337-51 Related articles (PubMed) Aghi M, et al. Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies. Cancer Res. 1999; 59(16):3861-5 Related articles (PubMed) Medline Search: (CYP2B1 OR CYP2B) AND cancer AND gene therapy (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to CYP2B Contents
CYP2B; Cytochrome P450, subfamily IIB (phenobarbital-inducible) (19q13.1-q13.2)
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Chemotherapy Resources