 Summary Information
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Location: 3p22-p21.3
Alias: CTNNB
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| Gene Database Entries for CTNNB1
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OMIM
GeneCard (Weizmann Institute)
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for CTNNB1)
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| Other Related Resources
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- Search Medline for related articles (PubMed)
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- Medline Search: cancer AND gene AND (CTNNB1[TI] OR CTNNB[TI]) (PubMed)
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| CTNNB1 and Carcinogenesis
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Kraus C, et al. Localization of the human beta-catenin gene (CTNNB1) to 3p21: a region implicated in tumor development. Genomics 1994; 23(1):272-4 Related articles (PubMed)
Takayama T, et al. Beta-catenin expression in human cancers. Am J Pathol 1996;148(1):39-46 Related articles (PubMed)
Medline Search: CTNNB1 AND cancer (PubMed)
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- Related Resources
 Resources by Disease Type
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| CTNNB1 and Colorectal Cancer
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Miyaki M, et al. Frequent mutation of beta-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer. Cancer Res 1999; 59(18):4506-9 Related articles (PubMed)
Ilyas M, et al. Beta-catenin mutations in cell lines established from human colorectal cancers. Proc Natl Acad Sci USA. 1997; 94(19):10330-4 Related articles (PubMed)
Medline Search: (beta catenin OR CTNNB1) AND colorectal cancer (PubMed)
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- APC gene
ColoRectal Cancers Genetics
ColoRectal Cancers : Clinical and Epidemiological Information
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| CTNNB1 and Liver Cancer
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| CTNNB1 and Hepatoblastoma
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Wei Y, et al. Activation of beta-catenin in epithelial and mesenchymal hepatoblastomas. Oncogene 2000 Jan 27;19(4):498-504 Related articles (PubMed)
Jeng YM, et al. Somatic mutations of beta-catenin play a crucial role in the tumorigenesis of sporadic hepatoblastoma. Cancer Lett 2000 Apr 28;152(1):45-51 Related articles (PubMed)
Koch A, et al. Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. Cancer Res. 1999 ; 59(2):269-73 Related articles (PubMed)
Blaker H, et al. Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma. Genes Chromosomes Cancer. 1999; 25(4):399-402 Related articles (PubMed)
Medline Search: (beta catenin OR CTNNB1) AND hepatoblastoma (PubMed)
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Hepatoblastoma Genetics
Hepatoblastoma : Clinical and Epidemiological Information
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| CTNNB1 and Hepatocellular Carcinoma
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Kondo Y, et al. Beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma. Jpn J Cancer Res 1999;90(12):1301-9 Related articles (PubMed)
Medline Search: (beta catenin OR CTNNB1) AND hepatocellular carcinoma (PubMed)
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- AXIN1 gene
Hepatocelular Carcinoma Genetics
Hepatocelular Carcinoma : Clinical and Epidemiological Information
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| CTNNB1 and Melanoma
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Rubinfeld B, et al. Stabilization of beta-catenin by genetic defects in melanoma cell lines. Science. 1997; 275(5307):1790-2 Related articles (PubMed)
Robbins PF, et al. A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes. J Exp Med. 1996;183(3):1185-92 Related articles (PubMed)
Medline Search: melanoma AND (beta catenin OR CTNNB1) (PubMed)
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Melanoma Genetics
Melanoma : Clinical and Epidemiological Information
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| CTNNB1 and Thyroid Cancer
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Garcia-Rostan G, et al. Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma. Cancer Res. 1999; 59(8):1811-5 Related articles (PubMed)
Cerrato A, et al. Beta- and gamma-catenin expression in thyroid carcinomas. J Pathol. 1998;185(3):267-72 Related articles (PubMed)
Medline Search: thyroid cancer AND (beta catenin OR CTNNB1) (PubMed)
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Thyroid Cancer Genetics
Thyroid Cancer : Clinical and Epidemiological Information
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| CTNNB1 and Ovarian Cancer
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Wright K, et al. beta-catenin mutation and expression analysis in ovarian cancer: exon 3 mutations and nuclear translocation in 16% of endometrioid tumours. Int J Cancer. 1999; 82(5):625-9 Related articles (PubMed)
Palacios J, et al. Mutations in the beta-catenin gene (CTNNB1) in endometrioid ovarian carcinomas. Cancer Res. 1998; 58(7):1344-7 Related articles (PubMed)
Medline Search: ovarian cancer AND (beta catenin OR CTNNB1) (PubMed)
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Ovarian Ca. Genetics
Ovarian Ca. : Clinical and Epidemiological Information
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| CTNNB1 and Prostate Cancer
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Voeller HJ, et al. Beta-catenin mutations in human prostate cancer. Cancer Res. 1998; 58(12):2520-3 Related articles (PubMed)
Medline Search: prostate cancer AND (beta catenin OR CTNNB1) (PubMed)
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Prostate Cancer Genetics
Prostate Cancer : Clinical and Epidemiological Information
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| CTNNB1 and Gastric Cancer
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Park WS, et al. Frequent somatic mutations of the beta-catenin gene in intestinal-type gastric cancer. Cancer Res 1999; 59(17):4257-60 Related articles (PubMed)
Medline Search: gastric cancer AND (beta catenin OR CTNNB1) (PubMed)
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Stomach (Gastric) Cancer Genetics
Stomach (Gastric) Cancer : Clinical and Epidemiological Information
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[Home] This page created: 28/10/1999 Last revised: 29/04/2003 © Copyright 1999-
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