Summary Information - BCL1
    Gene Database Entries for BCL1
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    BCL1 and Mantle Cell Lymphoma
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BCL1; B-cell CLL/lymphoma 1

Location: 11q13.3

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OMIM
GeneCard (Weizmann Institute)
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Tumor Gene Database
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for BCL1)

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Search Medline for related articles (PubMed)

Medline Search: cancer AND gene AND BCL1[TI] (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

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Related Resources
Mantle Cell Lymphoma Genetics

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Mantle cell lymphoma (MCL) is characterised by a t(11;14)(q13;q32) translocation. This juxtaposes the bcl-1 locus to the immunoglobulin (Ig) gene sequences and leads to deregulation of cyclin D1.

Espinet B, et al. Translocation (11;14)(q13;q32) and preferential involvement of chromosomes 1, 2, 9, 13, and 17 in mantle cell lymphoma. Cancer Genet Cytogenet. 1999; 111(1):92-8    Related articles (PubMed)

Stamatopoulos K, et al. Molecular analysis of bcl-1/IgH junctional sequences in mantle cell lymphoma: potential mechanism of the t(11;14) chromosomal translocation. Br J Haematol. 1999;105(1):190-7.    Related articles (PubMed)

Medline Search: mantle cell lymphoma and (cyclin D1 OR CCND1) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources

BCL1 gene

CCND1 gene
Mantle Cell Lymphoma Genetics

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