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CDK4; Cyclin-dependent kinase 4 (12q14)
CDK4 Menu

    Summary Information - CDK4
    Gene Database Entries for CDK4
    Other CDK4 Related Resources
    CDK4 Amplification in Sarcomas
       - CDK4 and Rhabdomyosarcoma
       - CDK4 Amplification in Osteosarcoma
    CDK4 Germline Mutations in Melanoma Prone Families
    Feedback / suggest a new topic for CDK4


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  Summary Information

CDK4; Cyclin-dependent kinase 4

Location: 12q14
Alias: PSK-J3

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  Gene Database Entries for CDK4

OMIM
GeneCard (Weizmann Institute)
Human Gene Mutation Database (Cardiff, UK)
Tumor Gene Database
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for CDK4)

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  Other Related Resources

Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (CDK4[TI] OR PSK-J3[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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      CDK4 Amplification in Sarcomas

  • Kanoe H, et al. Amplification of the CDK4 gene in sarcomas: tumor specificity and relationship with the RB gene mutation. Anticancer Res 1998 Jul-Aug;18(4A):2317-21    Related articles (PubMed)

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  •   CDK4 and Rhabdomyosarcoma

  • Khatib ZA, et al. Coamplification of the CDK4 gene with MDM2 and GLI in human sarcomas Cancer Res. 1993 Nov 15;53(22):5535-41    Related articles (PubMed)

  • Khan J, et al. Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays. Cancer Res 1998; 58(22):5009-13    Related articles (PubMed)

  • Medline Search: rhabdomyosarcoma AND CDK4 (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Childhood Soft Tissue Sarcoma Genetics
    Childhood Soft Tissue Sarcoma : Clinical and Epidemiological Information

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  •   CDK4 Amplification in Osteosarcoma

  • Wei G, et al. CDK4 gene amplification in osteosarcoma: reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons. Int J Cancer 1999 Jan 18;80(2):199-204    Related articles (PubMed)

  • Ragazzini P, et al. Analysis of SAS gene and CDK4 and MDM2 proteins in low-grade osteosarcoma Cancer Detect Prev 1999;23(2):129-36    Related articles (PubMed)

    Related Resources
    Osteosarcoma Genetics
    Osteosarcoma : Clinical and Epidemiological Information

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  •   CDK4 Germline Mutations in Melanoma Prone Families

  • Goldstein AM, et al. Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations. J Natl Cancer Inst 2000 Jun 21;92(12):1006-10    Related articles (PubMed)

  • Medline Search: cdk4 AND melanoma (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Melanoma Genetics
    Melanoma : Clinical and Epidemiological Information

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  •  [Home]   This page created: 09/10/1999  Last revised: 29/04/2003    © Copyright 1999-