 Summary Information
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Location: 6p21.2
Aliases: P21, WAF1
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| Gene Database Entries for CDKN1A
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OMIM
GeneCard (Weizmann Institute)
Human Gene Mutation Database (Cardiff, UK)
Tumor Gene Database
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for CDKN1A)
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| Other Related Resources
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- Search Medline for related articles (PubMed)
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- Medline Search: cancer AND gene AND (CDKN1A[TI] OR P21[TI] OR WAF1[TI]) (PubMed)
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| CDKN1A and Cancer
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Chang BD, et al. Effects of p21Waf1/Cip1/Sdi1 on cellular gene expression: implications for carcinogenesis, senescence, and age-related diseases. Proc Natl Acad Sci USA 2000; 97(8):4291-6 Related articles (PubMed)
Tsihlias J, et al. The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. [review] Annu Rev Med 1999;50:401-23 Related articles (PubMed)
- Related Resources
 Resources by Disease Type
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| CDKN1A Expression in Laryngeal Cancer
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Jeannon JP, et al. Expression of cyclin-dependent kinase inhibitor p21(WAF1) and p53 tumour suppressor gene in laryngeal cancer. Clin Otolaryngol 2000 Feb;25(1):23-7 Related articles (PubMed)
Hirvikoski P, et al. Downregulation of p21/WAF1 is related to advanced and dedifferentiated laryngeal squamous cell carcinoma. J Clin Pathol 1999 Jun;52(6):440-4 Related articles (PubMed)
Pruneri G, et al. Clinical relevance of expression of the CIP/KIP cell-cycle inhibitors p21 and p27 in laryngeal cancer. J Clin Oncol 1999 Oct;17(10):3150-9 Related articles (PubMed)
Medline Search: larngeal cancer AND (cdkn1a OR p21 OR waf1) (PubMed)
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Larynx, hypopharynx, oropharynx Ca. Genetics
Larynx, hypopharynx, oropharynx Ca. : Clinical and Epidemiological Information
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| CDKN1A Expression in Ovarian Cancer
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Anttila MA, et al. p21/WAF1 expression as related to p53, cell proliferation and prognosis in epithelial ovarian cancer. Br J Cancer 1999 Apr;79(11-12):1870-8 Related articles (PubMed)
Medline Search: ovarian cancer AND (cdkn1a OR p21 OR waf1) (PubMed)
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Ovarian Ca. Genetics
Ovarian Ca. : Clinical and Epidemiological Information
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| CDKN1A Expression in Prostate Cancer
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Aaltomaa S, et al. Prognostic value and expression of p21(waf1/cip1) protein in prostate cancer. Prostate 1999 Apr 1;39(1):8-15 Related articles (PubMed)
Medline Search: prostate cancer AND (cdkn1a OR p21 OR waf1) (PubMed)
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Prostate Cancer Genetics
Prostate Cancer : Clinical and Epidemiological Information
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| CDKN1A Expression in Colorectal Cancer
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Zirbes TK, et al. Prognostic impact of p21/waf1/cip1 in colorectal cancer. Int J Cancer 2000 Jan 20;89(1):14-8 Related articles (PubMed)
Medline Search: colon cancer AND (cdkn1a OR p21 OR waf1) (PubMed)
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ColoRectal Cancers Genetics
ColoRectal Cancers : Clinical and Epidemiological Information
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| CDKN1A Expression in Esophageal Cancer
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Natsugoe S, et al. Expression of p21WAF1/Cip1 in the p53-dependent pathway is related to prognosis in patients with advanced esophageal carcinoma. Clin Cancer Res 1999 Sep;5(9):2445-9 Related articles (PubMed)
Nita ME, et al. p21Waf1/Cip1 expression is a prognostic marker in curatively resected esophageal squamous cell carcinoma, but not p27Kip1, p53, or Rb. Ann Surg Oncol 1999 Jul-Aug;6(5):481-8 Related articles (PubMed)
Medline Search: esophageal cancer AND (cdkn1a OR p21 OR waf1) (PubMed)
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Stomach (Gastric) Cancer Genetics
Stomach (Gastric) Cancer : Clinical and Epidemiological Information
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| CDKN1A Expression in Bladder Cancer
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Medline Search: bladder cancer AND (cdkn1a OR p21 OR waf1) (PubMed)
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Bladder Ca. Genetics
Bladder Ca. : Clinical and Epidemiological Information
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[Home] This page created: 09/10/1999 Last revised: 29/04/2003 © Copyright 1999-
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