 Summary Information
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Location: 12p13
Aliases: KIP1, P27
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| Gene Database Entries for CDKN1B
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OMIM
GeneCard (Weizmann Institute)
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Tumor Gene Database
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for CDKN1B)
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| Other Related Resources
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- Search Medline for related articles (PubMed)
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- Medline Search: cancer AND gene AND (CDKN1B[TI] OR KIP1[TI] OR P27[TI]) (PubMed)
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| CDKN1B and Cancer
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Lloyd RV, et al. p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers. Am J Pathol 1999; 154(2):313-23 Related articles (PubMed)
Tsihlias J, et al. The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer. [review] Annu Rev Med 1999;50:401-23 Related articles (PubMed)
Medline Search: cancer AND (cdkn1b OR p27 OR kip1) (PubMed)
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- Related Resources
 Resources by Disease Type
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| CDKN1B and Breast Cancer
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Wu J, et al. Prognostic role of p27Kip1 and apoptosis in human breast cancer. Br J Cancer. 1999; 79(9-10):1572-8 Related articles (PubMed)
Tsuchiya A, et al. Prognostic impact of cyclin-dependent kinase inhibitor p27kip1 in node-positive breast cancer. J Surg Oncol. 1999; 70(4):230-4 Related articles (PubMed)
Fredersdorf S, et al. High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers. Proc Natl Acad Sci U S A. 1997; 94(12):6380-5 Related articles (PubMed)
Medline Search: breast cancer AND (cdkn1b OR p27 OR kip1) (PubMed)
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Breast Cancer Genetics
Breast Cancer : Clinical and Epidemiological Information
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| CDKN1B and Prostate Cancer
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Macri E, et al. Role of p27 in prostate carcinogenesis. [Review] Cancer Metastasis Rev. 1998-99;17(4):337-44 Related articles (PubMed)
Medline Search: prostate cancer AND (cdkn1b OR p27 OR kip1) (PubMed)
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Prostate Cancer Genetics
Prostate Cancer : Clinical and Epidemiological Information
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| CDKN1B and Colorectal Cancer
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Palmqvist R, et al. Prognostic significance of p27(Kip1) expression in colorectal cancer: a clinico-pathological characterization. J Pathol 1999; 188(1):18-23 Related articles (PubMed)
Fredersdorf S, et al. High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers. Proc Natl Acad Sci U S A. 1997; 94(12):6380-5 Related articles (PubMed)
Loda M, et al. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas Nat Med. 1997; 3(2):231-4 Related articles (PubMed)
Thomas GV, et al. Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases. Am J Pathol. 1998;153(3):681-7 Related articles (PubMed)
Medline Search: colorectal cancer AND (cdkn1b OR p27 OR kip1) (PubMed)
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ColoRectal Cancers Genetics
ColoRectal Cancers : Clinical and Epidemiological Information
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| CDKN1B and Ovarian Cancer
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Masciullo V, et al. Frequent loss of expression of the cyclin-dependent kinase inhibitor p27 in epithelial ovarian cancer. Cancer Res. 1999; 59(15):3790-4 Related articles (PubMed)
Sui L, et al. The concurrent expression of p27(kip1) and cyclin D1 in epithelial ovarian tumors. Gynecol Oncol. 1999; 73(2):202-9 Related articles (PubMed)
Medline Search: ovarian cancer AND (cdkn1b OR p27 OR kip1) (PubMed)
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Ovarian Ca. Genetics
Ovarian Ca. : Clinical and Epidemiological Information
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| CDKN1B and Gastric Cancer
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Ohtani M, et al. Impact of the expression of cyclin-dependent kinase inhibitor p27Kip1 and apoptosis in tumor cells on the overall survival of patients with non-early stage gastric carcinoma. Cancer. 1999; 85(8):1711-8 Related articles (PubMed)
Han S, et al. Expression of p27Kip1 and cyclin D1 proteins is inversely correlated and is associated with poor clinical outcome in human gastric cancer. J Surg Oncol. 1999; 71(3):147-54 Related articles (PubMed)
Yasui W, et al. Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas. Jpn J Cancer Res. 1997; 88(7):625-9 Related articles (PubMed)
Medline Search: gastric cancer AND (cdkn1b OR p27 OR kip1) (PubMed)
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Stomach (Gastric) Cancer Genetics
Stomach (Gastric) Cancer : Clinical and Epidemiological Information
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| CDKN1B and Bladder Cancer
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Del Pizzo JJ, et al. Loss of cell cycle regulators p27(Kip1) and cyclin E in transitional cell carcinoma of the bladder correlates with tumor grade and patient survival. Am J Pathol 1999; 155(4):1129-36 Related articles (PubMed)
Medline Search: bladder cancer AND (cdkn1b OR p27 OR kip1) (PubMed)
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Bladder Ca. Genetics
Bladder Ca. : Clinical and Epidemiological Information
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| CDKN1B Expression and Survival in Liposarcoma
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Oliveira AM, et al. p27kip1 Protein Expression Correlates With Survival in Myxoid and Round-Cell Liposarcoma J Clin Oncol 2000;18 2888-2893
- Related Resources
Soft Tissue Sarcoma : Clinical and Epidemiological Information
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[Home] This page created: 09/10/1999 Last revised: 29/04/2003 © Copyright 1999-
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