Summary Information - FKHR Gene Database Entries for FKHR Other FKHR Related Resources FKHR and Rhabdomyosarcoma - t(2;13)(q35;q14) in Rhabdomyosarcoma - t(1;13)(p36;q14) in Rhabdomyosarcoma Feedback / suggest a new topic for FKHR
FKHR; Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) Location: 13q14.1 Alias: FKH1 In aveolar rhabdomyosarcoma FKHR is frequently translocated with PAX3 or PAX7. Return to FKHR Contents
Location: 13q14.1 Alias: FKH1
In aveolar rhabdomyosarcoma FKHR is frequently translocated with PAX3 or PAX7.
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OMIM GeneCard (Weizmann Institute) Swiss-Prot Locus Link (search for FKHR) UniGene GenAtlas GDB Nomenclature (search for FKHR) Return to FKHR Contents
Search Medline for related articles (PubMed) Medline Search: cancer AND gene AND (FKHR[TI] OR FKH1[TI]) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to FKHR Contents
Bennicelli JL. et al. PAX3 and PAX7 exhibit conserved cis-acting transcription repression rhabdomyosarcoma. Oncogene 1999;18:4348-56 Related articles (PubMed) Barr FG The role of chimeric paired box transcription factors in the pathogenesis of pediatric rhabdomysarcoma. Cancer Res 1999; 59(7 Suppl):1711-5 Related articles (PubMed) Medline Search: FKHR AND rhabdomyosarcoma (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources PAX3 gene PAX7 gene Childhood Soft Tissue Sarcoma Genetics Childhood Soft Tissue Sarcoma : Clinical and Epidemiological Information Return to FKHR Contents
Alveolar rhabdomyosarcoma, a malignant tumour of skeletal muscle usually found in children and young adults, is characterised by a chromosomal translocation of the PAX3-FKHR genes: t(2;13)(q35;q14). Barr FG, et al. Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma. Nat Genet. 1993; 3:113-7 Related articles (PubMed) Shapiro DN, et al. Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma. Cancer Res. 1993; 53:5108-12 Related articles (PubMed) Bennicelli JL. et al. PAX3 and PAX7 exhibit conserved cis-acting transcription repression rhabdomyosarcoma. Oncogene 1999;18:4348-56 Related articles (PubMed) Barr FG The role of chimeric paired box transcription factors in the pathogenesis of pediatric rhabdomysarcoma. Cancer Res 1999; 59(7 Suppl):1711-5 Related articles (PubMed) Medline Search: rhabdomyosarcoma AND translocation AND chromosome 13 AND chromosome 2 (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources PAX3 gene FKHR gene Childhood Soft Tissue Sarcoma Genetics Childhood Soft Tissue Sarcoma : Clinical and Epidemiological Information Return to FKHR Contents
Bennicelli JL. et al. PAX3 and PAX7 exhibit conserved cis-acting transcription repression rhabdomyosarcoma. Oncogene 1999;18:4348-56 Related articles (PubMed) Barr FG The role of chimeric paired box transcription factors in the pathogenesis of pediatric rhabdomysarcoma. Cancer Res 1999; 59(7 Suppl):1711-5 Related articles (PubMed) Davis RJ, et al. Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res. 1994; 54:2869-72. Related articles (PubMed) Medline Search: rhabdomyosarcoma AND translocation AND chromosome 13 AND chromosome 1 (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources PAX7 gene FKHR gene Childhood Soft Tissue Sarcoma Genetics Childhood Soft Tissue Sarcoma : Clinical and Epidemiological Information Return to FKHR Contents
FKHR; Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) (13q14.1)
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PAX3 gene