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MADH4; Mothers against decapentaplegic, Drosophila (homolog 4) (18q21.1)
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    Summary Information - MADH4
    Gene Database Entries for MADH4
    Other MADH4 Related Resources
    MADH4 and Lung Cancer
    MADH4 and Colorectal Cancer
    MADH4 and Pancreatic Cancer
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  Summary Information

MADH4; Mothers against decapentaplegic, Drosophila (homolog 4)

Location: 18q21.1

Aliases: DPC4, SMAD4

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  Gene Database Entries for MADH4

OMIM
GeneCard (Weizmann Institute)
Human Gene Mutation Database (Cardiff, UK)
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for MADH4)

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  Other Related Resources


Cancer of the Pancreas and the DPC4 (Smad4) Gene (National Center for Biotechnology Information) an overview of cancer of the pancreas and the DPC4 oncogene with links to other gene databases.
Pancreatic Cancer Resources
Genetics / Familial Pancreatic Cancer

  • Medline Search: DPC4 (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
    Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (MADH4[TI] OR DPC4[TI] OR SMAD4[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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  •   MADH4 and Lung Cancer

  • Takei K, et al. A novel tumor suppressor locus on chromosome 18q involved in the development of human lung cancer. Cancer Res. 1998; 58(16):3700-5    Related articles (PubMed)

  • Nagatake M, et al. Somatic in vivo alterations of the DPC4 gene at 18q21 in human lung cancers Cancer Res. 1996; 56(12):2718-20.    Related articles (PubMed)

  • Medline Search: lung cancer AND (smad4 OR madh4 OR dpc4) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Lung Cancer Genetics
    Lung Cancer : Clinical and Epidemiological Information

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  •   MADH4 and Colorectal Cancer

  • Tarafa G, et al. DCC and SMAD4 alterations in human colorectal and pancreatic tumor dissemination. Oncogene 2000 Jan 27;19(4):546-55    Related articles (PubMed)

  • Koyama M, et al. Inactivation of both alleles of the DPC4/SMAD4 gene in advanced colorectal cancers: identification of seven novel somatic mutations in tumors from Japanese patients. Mutat Res. 1999;406(2-4):71-7.    Related articles (PubMed)

  • Medline Search: colorectal cancer AND (madh4 OR smad4 OR dpc4) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    ColoRectal Cancers Genetics
    ColoRectal Cancers : Clinical and Epidemiological Information

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  •   MADH4 and Pancreatic Cancer

  • Tarafa G, et al. DCC and SMAD4 alterations in human colorectal and pancreatic tumor dissemination. Oncogene 2000 Jan 27;19(4):546-55    Related articles (PubMed)

  • Schutte M DPC4/SMAD4 gene alterations in human cancer, and their functional implications.    Related articles (PubMed)

  • Medline Search: pancreatic cancer AND (madh4 OR smad4 OR dpc4) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Pancreatic Cancer Genetics
    Pancreatic Cancer : Clinical and Epidemiological Information

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