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  Uterus / Endometrium Cancer

Mutated Genes and Abnormal Protein Expression (7)
Overview of the Molecular Biology of Endometrial Cancer
Familial Cancers
Microsatellite Instability in Endometrial Cancer
Uterus / Endometrium Ca.: Clinical and Epidemiological Resources
  Mutated Genes and Abnormal Protein Expression
GeneLocationTopics
SLC2A1 ( GLUT1 ) 1p35-p31.3 -GLUT1 Overexpression in Endometrioid Carcinoma
MSH6 ( HNPCC5 , GTBP ) 2p16 -MSH6 and Endometrial Cancer
MSH35q11-q12  
PTEN ( MMAC1 , MHAM , BZS ) 10q23.3 -PTEN Mutations in Endometrial Cancer
-PTEN Mutations in Endometrial Precancers Lesions
KRAS2 ( Ki-ras , KRAS , K-RAS ) 12p12.1 -KRAS Mutations in Endometrial Cancer
RBL2 ( RB2 , P130 ) 16q12.2 -RBL2 and Endometrial Cancer
TP53 ( p53 , P53 ) 17p13.1 -TP53 Mutations in Endometrial Cancer

 

  Overview of the Molecular Biology of Endometrial Cancer

  • Sherman ME Theories of endometrial carcinogenesis: a multidisciplinary approach. [Review] Mod Pathol 2000;13(3):295-308    Related articles (PubMed)

  • Esteller M, et al. Advances in the molecular genetics of endometrial cancer. [Review] Oncol Rep 1999 Nov-Dec;6(6):1377-82    Related articles (PubMed)

  • Lax SF, et al. The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways. Cancer 2000 Feb 15;88(4):814-24    Related articles (PubMed)

  • Tibiletti MG, et al. Microsatellite instability in endometrial cancer: relation to histological subtypes. Gynecol Oncol 1999;73(2):247-52    Related articles (PubMed)

  • Medline Search: endometrial cancer AND genetics (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Uterus / Endometrium Ca. Genetics
    Uterus / Endometrium Ca. : Clinical and Epidemiological Information

     

  •   Familial Cancers

  • Hemminki K, et al. Endometrial cancer in the family-cancer database. Cancer Epidemiol Biomarkers Prev 1999;8(11):1005-10    Related articles (PubMed)

  • Kobayashi K, et al. Genetic analysis of familial and multiple malignancies of endometrial cancer. Int J Gynaecol Obstet 1999;66(2):149-53    Related articles (PubMed)

  • Berends MJ, et al. The importance of family history in young patients with endometrial cancer. Eur J Obstet Gynecol Reprod Biol 1999;82(2):139-41    Related articles (PubMed)

  • Medline Search: endometrial cancer AND familial cancer (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Uterus / Endometrium Ca. Genetics
    Uterus / Endometrium Ca. : Clinical and Epidemiological Information

     

  •   Microsatellite Instability in Endometrial Cancer

  • MacDonald ND, et al. Frequency and prognostic impact of microsatellite instability in a large population-based study of endometrial carcinomas. Cancer Res 2000 Mar 15;60(6):1750-2    Related articles (PubMed)

  • Tibiletti MG, et al. Microsatellite instability in endometrial cancer: relation to histological subtypes. Gynecol Oncol 1999;73(2):247-52    Related articles (PubMed)

    Uterus / Endometrium Ca. Genetics
    Uterus / Endometrium Ca. : Clinical and Epidemiological Information

     

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