 Summary Information
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Location: 10q25-qter
Alias: Ki-67
Involved in cell proliferation. It is expressed during the active phases of the cell cycle but absent in the G0 resting phase
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| Gene Database Entries for MKI67
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OMIM
GeneCard (Weizmann Institute)
Genbank
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for MKI67)
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| Other Related Resources
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- Search Medline for related articles (PubMed)
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- Medline Search: cancer AND gene AND (MKI67[TI] OR Ki-67[TI]) (PubMed)
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| Ki-67 and Cancer
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Scholzen T, Gerdes J The Ki-67 protein: from the known and the unknown. [Review] J Cell Physiol 2000 Mar;182(3):311-22 Related articles (PubMed)
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 Resources by Disease Type
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| Ki-67 and Breast Cancer Proliferation (MIB-1 assay)
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Thor AD, et al. Comparison of mitotic index, in vitro bromodeoxyuridine labeling, and MIB-1 assays to quantitate proliferation in breast cancer. J Clin Oncol 1999 Feb;17(2):470-7 Related articles (PubMed)
Pietilainen T, et al. The important prognostic value of Ki-67 expression as determined by image analysis in breast cancer. J Cancer Res Clin Oncol 1996;122(11):687-92 Related articles (PubMed)
Pinder SE, et al. Assessment of the new proliferation marker MIB1 in breast carcinoma using image analysis: associations with other prognostic factors and survival. Br J Cancer 1995 Jan;71(1):146-9 Related articles (PubMed)
Medline Search: ki-67 AND breast cancer (PubMed)
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Breast Cancer Genetics
Breast Cancer : Clinical and Epidemiological Information
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| Ki-67 Expression and Renal Cell Carcinoma
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Rioux-Leclercq N, et al. Value of immunohistochemical Ki-67 and p53 determinations as predictive factors of outcome in renal cell carcinoma. Urology 2000 Apr;55(4):501-5 Related articles (PubMed)
Aaltomaa S, et al Prognostic value of Ki-67 expression in renal cell carcinomas. Eur Urol 1997;31(3):350-5 Related articles (PubMed)
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| Ki-67 Expression in Prostate Cancer
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Matsuura H, et al. Prognostic significance of Ki-67 expression in advanced prostate cancers in relation to disease progression after androgen ablation. Eur Urol 2000 Feb;37(2):212-7 Related articles (PubMed)
Bubendorf L, et al. Ki67 labeling index in core needle biopsies independently predicts tumor-specific survival in prostate cancer. Hum Pathol 1998 Sep;29(9):949-54 Related articles (PubMed)
Masuda M, et al. Prognostic significance of Ki-67, p53, and Bcl-2 expression in prostate cancer patients with lymph node metastases: a retrospective immunohistochemical analysis. Pathol Int 1998 Jan;48(1):41-6 Related articles (PubMed)
Medline Search: ki-67 AND prostate cancer (PubMed)
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Prostate Cancer Genetics
Prostate Cancer : Clinical and Epidemiological Information
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[Home] This page created: 19/07/2000 Last revised: 04/03/2002 © Copyright 1999-
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