Childhood Brain Tumors

Overview

Literature Analysis

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Tag cloud generated 10 March, 2017 using data from PubMed, MeSH and CancerIndex

Mutated Genes and Abnormal Protein Expression (174)

How to use this data tableClicking on the Gene or Topic will take you to a separate more detailed page. Sort this list by clicking on a column heading e.g. 'Gene' or 'Topic'.

GeneLocationAliasesNotesTopicPapers
EGFR 7p12 ERBB, HER1, mENA, ERBB1, PIG61, NISBD2 -EGFR and Brain Tumours
616
TP53 17p13.1 P53, BCC7, LFS1, TRP53 -TP53 and Brain Tumours
612
MGMT 10q26 -MGMT and Brain Tumours
468
IDH1 2q33.3 IDH, IDP, IDCD, IDPC, PICD, HEL-216, HEL-S-26 -IDH1 and Brain Tumours
435
KITLG 12q22 SF, MGF, SCF, FPH2, FPHH, KL-1, Kitl, SHEP7 -KITLG and Brain Tumours
198
MKI67 10q26.2 KIA, MIB-, MIB-1, PPP1R105 -Ki-67 Antigen and Brain Tumours
179
GFAP 17q21 ALXDRD -GFAP and Brain Tumours
130
IDH2 15q26.1 IDH, IDP, IDHM, IDPM, ICD-M, D2HGA2, mNADP-IDH -IDH2 and Brain Tumours
117
NF1 17q11.2 WSS, NFNS, VRNF -NF1 and Brain Tumours
96
PROC 2q13-q14 PC, APC, PROC1, THPH3, THPH4 -PROC and Brain Tumours
68
SMARCB1 22q11.23 RDT, INI1, SNF5, Snr1, BAF47, MRD15, RTPS1, Sfh1p, hSNFS, SNF5L1, SWNTS1, PPP1R144 -SMARCB1 and Brain Tumours
65
NF2 22q12.2 ACN, SCH, BANF -NF2 and Brain Tumours
65
PDGFB 22q13.1 SIS, SSV, IBGC5, PDGF2, c-sis, PDGF-2 -PDGFB and Brain Tumours
48
CDKN2B 9p21 P15, MTS2, TP15, CDK4I, INK4B, p15INK4b -CDKN2B and Brain Tumours
47
OLIG2 21q22.11 BHLHB1, OLIGO2, RACK17, PRKCBP2, bHLHe19 -OLIG2 and Brain Tumours
40
TERT 5p15.33 TP2, TRT, CMM9, EST2, TCS1, hTRT, DKCA2, DKCB4, hEST2, PFBMFT1 -TERT and Brain Tumours
38
SOX2 3q26.3-q27 ANOP3, MCOPS3 -SOX2 and Brain Tumours
37
KIAA1549 7q34 -KIAA1549 and Brain Tumours
35
CIC 19q13.2 -CIC and Brain Tumours
34
PDGFRB 5q33.1 IMF1, IBGC4, JTK12, PDGFR, CD140B, PDGFR1, PDGFR-1 -PDGFRB and Brain Tumours
31
ATRX Xq21.1 JMS, SHS, XH2, XNP, ATR2, SFM1, MRX52, RAD54, MRXHF1, RAD54L, ZNF-HX -ATRX and Brain Tumours
29
KRIT1 7q21.2 CAM, CCM1 -KRIT1 and Brain Tumours
27
H3F3A 1q42.12 H3F3, H3.3A -H3F3A and Brain Tumours
23
IL13 5q31 P600, IL-13 -IL13 and Brain Tumours
23
IGFBP2 2q35 IBP2, IGF-BP53 -IGFBP2 and Brain Tumours
21
RAC1 7p22 MIG5, Rac-1, TC-25, p21-Rac1 -RAC1 and Brain Tumours
21
DONSON 21q22.1 B17, C21orf60 -DONSON and Brain Tumours
20
HES1 3q28-q29 HHL, HRY, HES-1, bHLHb39 -HES1 and Brain Tumours
17
SPARC 5q31.3-q32 ON -SPARC and Brain Tumours
17
RTEL1 20q13.3 NHL, RTEL, DKCA4, DKCB5, PFBMFT3, C20orf41 -RTEL1 and Brain Tumours
17
CD68 17p13 GP110, LAMP4, SCARD1 -CD68 and Brain Tumours
16
FUBP1 1p31.1 FBP, FUBP, hDH V -FUBP1 abnormalies in Oligodendroglioma and other Brain Tumours
15
CHI3L1 1q32.1 GP39, ASRT7, GP-39, YKL40, CGP-39, YKL-40, YYL-40, HC-gp39, HCGP-3P, hCGP-39 -CHI3L1 and Brain Tumours
15
SUFU 10q24.32 SUFUH, SUFUXL, PRO1280 -SUFU and Brain Tumours
14
CCDC26 8q24.21 RAM -CCDC26 and Brain Tumours
14
MDM4 1q32 HDMX, MDMX, MRP1 -MDM4 and Brain Tumours
12
PAX6 11p13 AN, AN2, FVH1, MGDA, WAGR, ASGD5, D11S812E -PAX6 and Brain Tumours
11
CCM2 7p13 OSM, C7orf22, PP10187 -CCM2 and Brain Tumours
11
PTK2 8q24.3 FAK, FADK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK -PTK2 and Brain Tumours
11
MIB1 18q11.2 MIB, DIP1, ZZZ6, DIP-1, LVNC7, ZZANK2 -MIB1 and Brain Tumours
11
ACVR1 2q23-q24 FOP, ALK2, SKR1, TSRI, ACTRI, ACVR1A, ACVRLK2 -ACVR1 and Brain Tumours
11
GDNF 5p13.1-p12 ATF1, ATF2, HSCR3, HFB1-GDNF -GDNF and Brain Tumours
11
PARK2 6q25.2-q27 PDJ, PRKN, AR-JP, LPRS2 -PARK2 and Brain Tumours
11
KLF6 10p15 GBF, ZF9, BCD1, CBA1, CPBP, PAC1, ST12, COPEB -KLF6 and Brain Tumours
11
OTX2 14q22.3 CPHD6, MCOPS5 -OTX2 and Brain Tumours
10
PLK1 16p12.2 PLK, STPK13 -PLK1 and Brain Tumours
10
MTAP 9p21 BDMF, MSAP, DMSFH, LGMBF, DMSMFH, c86fus, HEL-249 -MTAP and Brain Tumours
10
PRKDC 8q11 HYRC, p350, DNAPK, DNPK1, HYRC1, IMD26, XRCC7, DNA-PKcs -PRKDC and Brain Tumours
9
MELK 9p13.2 HPK38 -MELK and Brain Tumours
9
PDCD10 3q26.1 CCM3, TFAR15 -PDCD10 and Brain Tumours
9
YAP1 11q22.1 YAP, YKI, COB1, YAP2, YAP65 -YAP1 and Brain Tumours
9
NGFR 17q21-q22 CD271, p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR -NGFR and Brain Tumours
9
PRINS 10p12.1 NCRNA00074 -PRINS and Brain Tumours
8
NKX2-2 20p11.22 NKX2B, NKX2.2 -NKX2-2 and Brain Tumours
8
SST 3q28 SMST -SST and Brain Tumours
8
MSI1 12q24 -MSI1 and Brain Tumours
8
MAP2 2q34-q35 MAP2A, MAP2B, MAP2C -MAP2 and Brain Tumours
7
APOE 19q13.2 AD2, LPG, APO-E, LDLCQ5 -APOE and Brain Tumours
7
PON1 7q21.3 ESA, PON, MVCD5 -PON1 and Brain Tumours
7
IL13RA1 Xq24 NR4, CT19, CD213A1, IL-13Ra -IL13RA1 and Brain Tumours
7
BDNF 11p14.1 ANON2, BULN2 -BDNF and Brain Tumours
7
DAXX 6p21.3 DAP6, EAP1, BING2 -DAXX and Brain Tumours
6
PDPN 1p36.21 T1A, GP36, GP40, Gp38, OTS8, T1A2, TI1A, T1A-2, AGGRUS, HT1A-1, PA2.26 -PDPN and Brain Tumours
6
SOX10 22q13.1 DOM, WS4, PCWH, WS2E, WS4C -SOX10 and Brain Tumours
6
HSPB1 7q11.23 CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.76067, HEL-S-102 -HSPB1 and Brain Tumours
6
MIF 22q11.23 GIF, GLIF, MMIF -MIF and Brain Tumours
6
PEG3 19q13.4 PW1, ZNF904, ZSCAN24, ZKSCAN22 -PEG3 and Brain Tumours
6
TGFB2 1q41 LDS4, TGF-beta2 -TGFB2 and Brain Tumours
6
ADGRB1 8q24.3 BAI1, GDAIF -BAI1 and Brain Tumours
6
TFPI 2q32 EPI, TFI, LACI, TFPI1 -TFPI and Brain Tumours
5
FABP7 6q22-q23 MRG, BLBP, FABPB, B-FABP, LTR2-FABP7 -FABP7 and Brain Tumours
5
LRIG3 12q14.1 LIG3 -LRIG3 and Brain Tumours
5
PIK3R1 5q13.1 p85, AGM7, GRB1, IMD36, p85-ALPHA -PIK3R1 and Brain Tumours
5
LRIG1 3p14 LIG1, LIG-1 -LRIG1 and Brain Tumours
5
DLL4 15q14 hdelta2 -DLL4 and Brain Tumours
5
PYCARD 16p11.2 ASC, TMS, TMS1, CARD5, TMS-1 -PYCARD and Brain Tumours
5
MTDH 8q22.1 3D3, AEG1, AEG-1, LYRIC, LYRIC/3D3 -MTDH and Brain Tumours
5
FOXG1 14q13 BF1, BF2, QIN, FKH2, HBF2, HFK1, HFK2, HFK3, KHL2, FHKL3, FKHL1, FKHL2, FKHL3, FKHL4, HBF-1, HBF-2, HBF-3, FOXG1A, FOXG1B, FOXG1C, HBF-G2 -FOXG1 and Brain Tumours
5
PTPRF 1p34 LAR, BNAH2 -PTPRF and Brain Tumours
5
LIN28B 6q21 CSDD2 -LIN28B and Brain Tumours
5
LDHA 11p15.1 LDHM, GSD11, PIG19, HEL-S-133P -LDHA and Brain Tumours
5
TUBB3 16q24.3 CDCBM, FEOM3, TUBB4, CDCBM1, CFEOM3, beta-4, CFEOM3A -TUBB3 and Brain Tumours
5
AQP1 7p14 CO, CHIP28, AQP-CHIP -AQP1 and Brain Tumours
4
JAG1 20p12.1-p11.23 AGS, AHD, AWS, HJ1, CD339, JAGL1 -JAG1 and Brain Tumours
4
LGI1 10q24 EPT, ETL1, ADLTE, ADPAEF, ADPEAF, IB1099, EPITEMPIN -LGI1 and Brain Tumours
4
RAC2 22q13.1 Gx, EN-7, HSPC022, p21-Rac2 -RAC2 and Brain Tumours
4
PDGFA 7p22 PDGF1, PDGF-A -PDGFA and Childhood Brain Tumours
4
APCS 1q21-q23 SAP, PTX2, HEL-S-92n -APCS and Brain Tumours
4
MERTK 2q14.1 MER, RP38, c-Eyk, c-mer, Tyro12 -MERTK and Brain Tumours
4
SOX5 12p12.1 L-SOX5, L-SOX5B, L-SOX5F -SOX5 and Brain Tumours
4
CD151 11p15.5 GP27, MER2, RAPH, SFA1, PETA-3, TSPAN24 -CD151 and Brain Tumours
4
TACC3 4p16.3 ERIC1, ERIC-1 -TACC3 and Brain Tumours
4
NDRG2 14q11.2 SYLD -NDRG2 and Brain Tumours
4
EFEMP1 2p16 DHRD, DRAD, FBNL, MLVT, MTLV, S1-5, FBLN3, FIBL-3 -EFEMP1 and Brain Tumours
4
CNTF 11q12.1 HCNTF -CNTF and Brain Tumours
4
LIG4 13q33-q34 LIG4S -LIG4 and Brain Tumours
4
SMAD6 15q22.31 AOVD2, MADH6, MADH7, HsT17432 -SMAD6 and Brain Tumours
4
MIR124-1 8p23.1 MIR124A, MIR124A1, MIRN124-1, MIRN124A1, mir-124-1 -microRNA 124-1 and Brain Tumours
4
YBX1 1p34 YB1, BP-8, CSDB, DBPB, YB-1, CSDA2, NSEP1, NSEP-1, MDR-NF1 -YBX1 and Brain Tumours
4
BCHE 3q26.1-q26.2 E1, CHE1, CHE2 -BCHE and Brain Tumours
4
SNAI2 8q11 SLUG, WS2D, SLUGH1, SNAIL2 -SNAI2 and Brain Tumours
4
BUB3 10q26 BUB3L, hBUB3 -BUB3 and Brain Tumours
4
EPHB6 7q33-q35 HEP -EPHB6 and Brain Tumours
4
MIR107 10q23.31 MIRN107, miR-107 -MicroRNA mir-107 and Brain Tumours
4
ANGPT1 8q23.1 AGP1, AGPT, ANG1 -ANGPT1 and Brain Tumours
4
ADARB1 21q22.3 RED1, ADAR2, DRABA2, DRADA2 -ADARB1 and Brain Tumours
4
MYBL1 8q13.1 AMYB, A-MYB -MYBL1 and Brain Tumours
4
SMAD5 5q31 DWFC, JV5-1, MADH5 -SMAD5 and Brain Tumours
4
GLIPR1 12q21.2 GLIPR, RTVP1, CRISP7 -GLIPR1 and Brain Tumours
3
GNAI2 3p21.31 GIP, GNAI2B, H_LUCA15.1, H_LUCA16.1 -GNAI2 and Brain Tumours
3
CX3CL1 16q13 NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin -CX3CL1 and Brain Tumours
3
CCNG2 4q21.1 -CCNG2 and Brain Tumours
3
SEPT7 7p14.2 CDC3, CDC10, SEPT7A, NBLA02942 -SEPT7 and Brain Tumours
3
NFKBIA 14q13 IKBA, MAD-3, NFKBI -NFKBIA and Brain Tumours
3
PMP22 17p12 DSS, HNPP, CMT1A, CMT1E, GAS-3, Sp110, HMSNIA -PMP22 and Brain Tumours
3
GLTSCR2 19q13.3 PICT1, PICT-1 -GLTSCR2 and Brain Tumours
3
GFRA1 10q26.11 GDNFR, RET1L, RETL1, TRNR1, GDNFRA, GFR-ALPHA-1 -GFRA1 and Brain Tumours
3
RAP2A 13q34 KREV, RAP2, K-REV, RbBP-30 -RAP2A and Brain Tumours
3
WNT5B 12p13.3 -WNT5B and Brain Tumours
3
RBP1 3q23 CRBP, RBPC, CRBP1, CRBPI, CRABP-I -RBP1 and Brain Tumours
3
STIM1 11p15.4 GOK, TAM, TAM1, IMD10, STRMK, D11S4896E -STIM1 and Brain Tumours
3
PIK3CD 1p36.2 APDS, PI3K, IMD14, p110D, P110DELTA -PIK3CD and Brain Tumours
3
ANXA7 10q22.2 SNX, ANX7, SYNEXIN -ANXA7 and Brain Tumours
3
NEURL1 10q25.1 neu, NEUR1, NEURL, RNF67, neu-1, bA416N2.1 -NEURL and Brain Tumours
3
KLK6 19q13.3 hK6, Bssp, Klk7, SP59, PRSS9, PRSS18 -KLK6 and Brain Tumours
3
MAML1 5q35 Mam1, Mam-1 -MAML1 and Brain Tumours
3
POLI 18q21.1 RAD30B, RAD3OB -POLI and Brain Tumours
3
IL4R 16p12.1-p11.2 CD124, IL4RA, IL-4RA -IL4R and Brain Tumours
3
COL4A2 13q34 ICH, POREN2 -COL4A2 and Brain Tumours
3
FMR1 Xq27.3 POF, FMRP, POF1, FRAXA -FMR1 and Brain Tumours
3
CX3CR1 3p21.3 V28, CCRL1, GPR13, CMKDR1, GPRV28, CMKBRL1 -CX3CR1 and Brain Tumours
3
MVP 16p11.2 LRP, VAULT1 -MVP and Brain Tumours
3
UPRT Xq13.3 UPP, FUR1 -UPRT and Brain Tumours
2
PEA15 1q21.1 PED, MAT1, HMAT1, MAT1H, PEA-15, HUMMAT1H -PEA15 and Brain Tumours
2
YEATS4 12q15 YAF9, GAS41, NUBI-1, 4930573H17Rik, B230215M10Rik -YEATS4 and Brain Tumours
2
PRKCDBP 11p15.4 SRBC, HSRBC, CAVIN3, cavin-3 -PRKCDBP and Brain Tumours
2
SDC4 20q12 SYND4 -SDC4 and Brain Tumours
2
RASSF10 11p15.3 -RASSF10 and Brain Tumours
2
CBX7 22q13.1 -CBX7 and Brain Tumours
2
POU2F2 19q13.2 OCT2, OTF2, Oct-2 -POU2F2 and Brain Tumours
2
ENO1 1p36.2 NNE, PPH, MPB1, ENO1L1 -ENO1 and Brain Tumours
2
VCAM1 1p32-p31 CD106, INCAM-100 -VCAM1 and Brain Tumours
2
KRT8 12q13 K8, KO, CK8, CK-8, CYK8, K2C8, CARD2 -KRT8 and Brain Tumours
2
CAMTA1 1p36.31-p36.23 CANPMR -CAMTA1 and Brain Tumours
2
ADAR 1q21.3 DSH, AGS6, G1P1, IFI4, P136, ADAR1, DRADA, DSRAD, IFI-4, K88DSRBP -ADAR and Brain Tumours
2
TNKS 8p23.1 TIN1, ARTD5, PARPL, TINF1, TNKS1, pART5, PARP5A, PARP-5a -TNKS and Brain Tumours
2
IL24 1q32 C49A, FISP, MDA7, MOB5, ST16, IL10B -IL24 and Brain Tumours
2
WNT10B 12q13 SHFM6, WNT-12 -WNT10B and Brain Tumours
2
ASPSCR1 17q25.3 TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1 -ASPSCR1 and Brain Tumours
2
FTL 19q13.33 LFTD, NBIA3 -FTL and Brain Tumours
2
ELN 7q11.23 WS, WBS, SVAS -ELN and Brain Tumours
2
KDM5B 1q32.1 CT31, PLU1, PUT1, PLU-1, JARID1B, PPP1R98, RBBP2H1A -KDM5B and Brain Tumours
2
RAD17 5q13 CCYC, R24L, RAD24, HRAD17, RAD17SP -RAD17 and Brain Tumours
2
CSTB 21q22.3 PME, ULD, CST6, EPM1, STFB, EPM1A -CSTB and Brain Tumours
2
NRP2 2q33.3 NP2, NPN2, PRO2714, VEGF165R2 -NRP2 and Brain Tumours
2
TYRO3 15q15 BYK, Dtk, RSE, Rek, Sky, Tif, Etk-2 -TYRO3 and Brain Tumours
2
SOX6 11p15.2 SOXD, HSSOX6 -SOX6 and Brain Tumours
1
CD1D 1q23.1 R3, CD1A -CD1D and Brain Tumours
1
PIK3R2 19q13.2-q13.4 p85, MPPH, P85B, MPPH1, p85-BETA -PIK3R2 and Brain Tumours
1
IL1RL1 2q12 T1, ST2, DER4, ST2L, ST2V, FIT-1, IL33R -IL1RL1 and Brain Tumours
1
STARD13 13q13.1 DLC2, GT650, ARHGAP37, LINC00464 -STARD13 and Brain Tumours
1
ARHGAP26 5q31 GRAF, GRAF1, OPHN1L, OPHN1L1 -ARHGAP26 and Brain Tumours
1
MIR1258 2q31.3 MIRN1258, mir-1258, hsa-mir-1258 -MicroRNA miR-1258 and Brain Tumours
1
CCNB1IP1 14q11.2 HEI10, C14orf18 -CCNB1IP1 and Brain Tumours
1
MIR10A 17q21.32 MIRN10A, mir-10a, miRNA10A, hsa-mir-10a -MIR10A and Brain Tumours
1
RNF213 17q25.3 ALO17, MYMY2, MYSTR, NET57, C17orf27, KIAA1618 -RNF213 and Brain Tumours
1
EPHA5 4q13.1 EK7, CEK7, EHK1, HEK7, EHK-1, TYRO4 -EPHA5 and Brain Tumours
1
ENDOU 12q13.1 P11, PP11, PRSS26 -ENDOU and Brain Tumours
1
SRGAP3 3p25.3 WRP, MEGAP, SRGAP2, ARHGAP14 -SRGAP3 and Brain Tumours
1
RASSF7 11p15.5 HRC1, HRAS1, C11orf13 -RASSF7 and Brain Tumours
1
ST2 11p14.3-p12 -ST2 and Brain Tumours
1
ANP32A 15q23 LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1 -ANP32A and Brain Tumours
1
FSTL3 19p13 FLRG, FSRP -FSTL3 and Brain Tumours
PTPRT 20q12-q13 RPTPrho -PTPRT and Brain Tumours

Note: list is not exhaustive. Number of papers are based on searches of PubMed (click on topic title for arbitrary criteria used).

Disclaimer: This site is for educational purposes only; it can not be used in diagnosis or treatment.

Cite this page: Cotterill SJ. Childhood Brain Tumors, Cancer Genetics Web: http://www.cancer-genetics.org/X0302.htm Accessed:

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