www.Cancer-Genetics.org
Navigate
  Chromosome 9

Genes Linked with Cancer

How to use this data table Click on the gene name for detailed information. Type in the Search box e.g. 'germline' or 'Breast Cancer' to search within Chromosome 9; or Sort by clicking on a column heading e.g. 'Gene'.

Gene Location Aliases Abnormalities Implicated in
BAG1 9p12 HAP, BAG-1, RAP46OverexpressionMany cancer types including:
-Bowel Cancer
-Breast Cancer
-Endometrial Cancer
-Prostate Cancer
-Apoptosis
FANCG 9p13 FAG, XRCC9Germline-Fanconi Anaemia
PAX5 9p13 BSAPGermline & Somatic
Translocation
-Acute Lymphocytic Leukemia (ALL), child
-Lymphoma
CCL21 9p13 ECL, SLC, CKb9, TCA4, 6Ckine, SCYA21
CDKN2A 9p21 ARF, MLM, P14, P16, P19, CMM2, INK4, MTS1, TP16, CDK4I, CDKN2, INK4A, MTS-1, P14ARF, P19ARF, P16INK4, P16INK4A, P16-INK4AGermline & Somatic
Deletion
-Ewing's Sarcoma
CDKN2B 9p21 P15, MTS2, TP15, CDK4I, INK4B, p15INK4b
MLLT3 9p22 AF9, YEATS3Somatic
Translocation
-Acute Myeloid Leukaemia
PSIP1 9p22.3 p52, p75, PAIP, DFS70, LEDGF, PSIP2Somatic
JAK2 9p24 JTK10, THCYT3Somatic
CD274 9p24 B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1Somatic
NFIB 9p24.1 CTF, NF1-B, NFI-B, NFIB2, NFIB3, NF-I/B, NFI-RED, HMGIC/NFIBSomatic
PDCD1LG2 9p24.2 B7DC, Btdc, PDL2, CD273, PD-L2, PDCD1L2, bA574F11.2Somatic
GNAQ 9q21 GAQ, SWS, CMC1, G-ALPHA-qSomatic
ALDH1A1 9q21.13 ALDC, ALDH1, HEL-9, HEL12, PUMB1, ALDH11, RALDH1, ALDH-E1, HEL-S-53e
RMI1 9q21.32 BLAP75, FAAP75, C9orf76, RP11-346I8.1
NR4A3 9q22 CHN, TEC, CSMF, NOR1, MINORSomatic
Translocation
-Chondrosarcoma
TGFBR1 9q22 AAT5, ALK5, ESS1, MSSE, SKR4, ALK-5, LDS1A, LDS2A, TGFR-1, ACVRLK4-Bladder Cancer
-Bowel Cancer
-Breast Cancer
-Pancreatic Cancer
-Skin Cancer
SYK 9q22 p72-SykSomatic
NTRK2 9q22.1 TRKB, trk-B, GP145-TrkB-Cervical Cancer
-Neuroblastoma
-Oral Cavity Cancer
-Wilms Tumour
XPA 9q22.3 XP1, XPAC, RP11-244N9.4Germline
FANCC 9q22.3 FA3, FAC, FACCGermline-Fanconi Anaemia
PTCH1 9q22.3 PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11Germline & Somatic
OMD 9q22.31 OSAD, SLRR2CSomatic
DEC1 9q32 CTS9
TNFSF15 9q32 TL1, TL1A, VEGI, VEGI192A-Bladder Cancer
-Breast Cancer
-Kidney Cancer
TAL2 9q32 Somatic
BRINP1 9q32-q33 DBC1, FAM5A, DBCCR1
CNTRL 9q33.2 FAN, CEP1, CEP110, bA165P4.1Somatic
TSC1 9q34 LAM, TSCGermline
BRD3 9q34 ORFX, RING3LSomatic
FNBP1 9q34 FBP17Somatic
SET 9q34 2PP2A, IGAAD, TAF-I, I2PP2A, IPP2A2, PHAPII, TAF-IBETASomatic
Translocation
-Acute Myeloid Leukaemia
-Wilms Tumour
ABL1 9q34.1 ABL, JTK7, p150, c-ABL, v-abl, c-ABL1, bcr/ablSomatic
Translocation
-Acute Lymphocytic Leukaemia (ALL) - adult
-Chronic Myelogenous Leukemia
NUP214 9q34.1 CAN, CAIN, N214, p250, D9S46ESomatic
Translocation
-Acute Lymphocytic Leukaemia (ALL) - adult
-Acute Myeloid Leukaemia
RAPGEF1 9q34.3 C3G, GRF2
RXRA 9q34.3 NR2B1
NOTCH1 9q34.3 hN1, TAN1Somatic
Translocation
-Acute Lymphocytic Leukaemia (ALL) - adult
-Acute Lymphocytic Leukemia (ALL), child
-Breast Cancer
-Childhood Cancers
-Chronic Lymphocytic Leukemia
-Head and Neck Cancers
-Thyroid Cancer
RALGDS 9q34.3 RGF, RGDS, RalGEFSomatic

Structural Abnormalities

Selected list of common recurrent structural abnormalities - Chromosome 9:

Abnormality Type Gene(s)
del(9p) in Lung CancerDeletion
del(9p) in NeuroblastomaDeletion
del(9q) in Bladder CancerDeletion