Chromosome 9

Genes Linked with Cancer (82)

How to use this data table Click on the gene name for detailed information. Type in the Search box e.g. 'germline' or 'Breast Cancer' to search within Chromosome 9; or Sort by clicking on a column heading e.g. 'Gene'.

Gene Location Aliases Abnormalities Implicated in
BAG1 9p12 HAP, BAG-1, RAP46OverexpressionMany cancer types including:
-Breast Cancer
-Colorectal Cancer
-Endometrial Cancer
-Prostate Cancer
-Apoptosis
FANCG 9p13 FAG, XRCC9Germline-Fanconi Anaemia
GALT 9p13 -Breast Cancer
-Ovarian Cancer
PAX5 9p13 ALL3, BSAPGermline & Somatic
Translocation
-Acute Lymphocytic Leukemia (ALL), child
-Lymphoma
CCL21 9p13 ECL, SLC, CKb9, TCA4, 6Ckine, SCYA21-Breast Cancer
-Colorectal Cancer
CCL19 9p13 ELC, CKb11, MIP3B, MIP-3b, SCYA19-Chronic Lymphocytic Leukemia
-Colorectal Cancer
-Head and Neck Cancers
-Lung Cancer
-Lung Cancer, Non-Small Cell
-Skin Cancer
AQP3 9p13 GIL, AQP-3-Cervical Cancer
-Esophageal Cancer
-Lung Cancer
-Melanoma
-Skin Cancer
-Stomach Cancer
MELK 9p13.2 HPK38-Brain Tumours, Childhood
-Breast Cancer
RECK 9p13.3 ST15-Cervical Cancer
-Lung Cancer
-Lung Cancer, Non-Small Cell
-Prostate Cancer
CA9 9p13.3 MN, CAIX-Cervical Cancer
-Kidney Cancer
-Oral Cavity Cancer
-Thyroid Cancer
-von Hippel-Lindau Disease
-Vulvar Cancer
MTAP 9p21 BDMF, MSAP, DMSFH, LGMBF, DMSMFH, c86fus, HEL-249-Acute Lymphocytic Leukaemia (ALL)
-Brain Tumours, Childhood
-Lung Cancer
-Lung Cancer, Non-Small Cell
-Melanoma
CDKN2A 9p21 ARF, MLM, P14, P16, P19, CMM2, INK4, MTS1, TP16, CDK4I, CDKN2, INK4A, MTS-1, P14ARF, P19ARF, P16INK4, P16INK4A, P16-INK4AGermline & Somatic
Deletion
-Adrenocortical Cancer
-Bladder Cancer
-Breast Cancer
-Colorectal Cancer
-Ewing's Sarcoma
-Head and Neck Cancers
-Hodgkin Lymphoma
-Lung Cancer
-Melanoma
-Familial Melanoma
-Mesothelioma
-Neurofibromatosis
-Osteosarcoma
-Pancreatic Cancer
-Familial Pancreatic Cancer
-Rhabdomyosarcoma
-Wilms Tumour
RPS6 9p21 S6-Astrocytoma, Childhood
-Liver Cancer
-Oral Cavity Cancer
-Pancreatic Cancer
CDKN2B 9p21 P15, MTS2, TP15, CDK4I, INK4B, p15INK4b-Acute Lymphocytic Leukaemia (ALL)
-Bladder Cancer
-Brain Tumours, Childhood
CDKN2B-AS1 9p21.3 ANRIL, p15AS, PCAT12, CDKN2BAS, CDKN2B-AS, NCRNA00089Germline
IFNA17 9p22 IFNA, INFA, LEIF2C1, IFN-alphaI-Acute Lymphocytic Leukaemia (ALL)
-Chronic Myelogenous Leukemia
-Kidney Cancer
-Liver Cancer
-Multiple Myeloma
IFNA2 9p22 IFNA, INFA2, IFNA2B, IFN-alphaA-Acute Lymphocytic Leukaemia (ALL)
-Chronic Myelogenous Leukemia
-Kidney Cancer
-Liver Cancer
-Multiple Myeloma
IFNA7 9p22 IFNA-J, IFN-alphaJ-Acute Lymphocytic Leukaemia (ALL)
-Chronic Myelogenous Leukemia
-Kidney Cancer
-Liver Cancer
-Multiple Myeloma
MLLT3 9p22 AF9, YEATS3Somatic
Translocation
-Acute Lymphocytic Leukaemia (ALL)
-Acute Myeloid Leukaemia
-Leukaemia
PSIP1 9p22.3 p52, p75, PAIP, DFS70, LEDGF, PSIP2Somatic-Acute Myeloid Leukaemia
-Bladder Cancer
-Leukaemia
SMARCA2 9p22.3 BRM, SNF2, SWI2, hBRM, NCBRS, Sth1p, BAF190, SNF2L2, SNF2LA, hSNF2a-Bladder Cancer
-Breast Cancer
-Lung Cancer
-Lung Cancer, Non-Small Cell
-Melanoma
TYRP1 9p23 TRP, CAS2, CATB, GP75, OCA3, TRP1, TYRP, b-PROTEIN-Eye Cancer
-Melanoma
-Skin Cancer
PTPRD 9p23-p24.3 HPTP, PTPD, HPTPD, HPTPDELTA, RPTPDELTA-Lung Cancer
-Melanoma
CD274 9p24 B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1Somatic-Melanoma
-Stomach Cancer
JAK2 9p24 JTK10, THCYT3Somatic-Acute Lymphocytic Leukaemia (ALL)
-Leukaemia
-Myeloproliferative Disorders
-Skin Cancer
-Stomach Cancer
NFIB 9p24.1 CTF, NF1-B, NFI-B, NFIB2, NFIB3, NF-I/B, NFI-RED, HMGIC/NFIBSomatic-Adenoid Cystic Carcinoma
-Breast Cancer
-Head and Neck Cancers
-Small Cell Lung Cancer
-Salivary Gland Cancer
KDM4C 9p24.1 GASC1, JHDM3C, JMJD2C, TDRD14C, bA146B14.1-Acute Myeloid Leukaemia
-Breast Cancer
-Esophageal Cancer
-Prostate Cancer
MLANA 9p24.1 MART1, MART-1-Kaposi Sarcoma
-Melanoma
PDCD1LG2 9p24.2 B7DC, Btdc, PDL2, CD273, PD-L2, PDCD1L2, bA574F11.2Somatic-Acute Myeloid Leukaemia
-Chronic Myelogenous Leukemia
-Hodgkin Lymphoma
-Stomach Cancer
GNAQ 9q21 GAQ, SWS, CMC1, G-ALPHA-qSomatic-Eye Cancer
-Melanoma
ALDH1A1 9q21.13 ALDC, ALDH1, HEL-9, HEL12, PUMB1, ALDH11, RALDH1, ALDH-E1, HEL-S-53e-Breast Cancer
-Lung Cancer
ANXA1 9q21.13 ANX1, LPC1-Bladder Cancer
-Breast Cancer
-Stomach Cancer
PCA3 9q21.2 DD3, PCAT3, NCRNA00019-Cancer Screening
-Prostate Cancer
GAS1 9q21.3-q22 -Brain Stem Glioma, Childhood
-Prostate Cancer
-Uterine Sarcoma
RMI1 9q21.32 BLAP75, FAAP75, C9orf76-Acute Myeloid Leukaemia
-Bone Cancer (primary)
-Osteosarcoma
-Prostate Cancer
-Skin Cancer
TLE1 9q21.32 ESG, ESG1, GRG1-Acute Myeloid Leukaemia
-Breast Cancer
-Cervical Cancer
-Soft Tissue Sarcoma
-Synovial Sarcoma
CTSL 9q21.33 MEP, CATL, CTSL1-Breast Cancer
-Esophageal Cancer
-Melanoma
-Osteosarcoma
-Thyroid Cancer
DAPK1 9q21.33 DAPK-Bladder Cancer
-Cervical Cancer
-Chronic Lymphocytic Leukemia
-Skin Cancer
-Soft Tissue Sarcoma
-Stomach Cancer
-Thyroid Cancer
-Urinary System Cancers
ROR2 9q22 BDB, BDB1, NTRKR2-Chronic Lymphocytic Leukemia
-Lung Cancer
-Stomach Cancer
TGFBR1 9q22 AAT5, ALK5, ESS1, LDS1, MSSE, SKR4, ALK-5, LDS1A, LDS2A, TGFR-1, ACVRLK4, tbetaR-I-Bladder Cancer
-Breast Cancer
-Colorectal Cancer
-Pancreatic Cancer
-Skin Cancer
CKS2 9q22 CKSHS2-Bladder Cancer
-Cervical Cancer
-Colorectal Cancer
-Esophageal Cancer
-Liver Cancer
-Prostate Cancer
NR4A3 9q22 CHN, TEC, CSMF, NOR1, MINORSomatic
Translocation
-Bone Cancer (primary)
-Cervical Cancer
-Chondrosarcoma
-Soft Tissue Sarcoma
FOXE1 9q22 TTF2, FOXE2, HFKH4, HFKL5, TITF2, TTF-2, FKHL15-Pancreatic Cancer
-Skin Cancer
SYK 9q22 p72-SykSomatic-Breast Cancer
-Chronic Lymphocytic Leukemia
NTRK2 9q22.1 TRKB, trk-B, GP145-TrkB-Cervical Cancer
-Neuroblastoma
-Oral Cavity Cancer
-Wilms Tumour
FANCC 9q22.3 FA3, FAC, FACCGermline-Fanconi Anaemia
PTCH1 9q22.3 PTC, BCNS, HPE7, PTC1, PTCH, NBCCS, PTCH11Germline & Somatic-Basal Cell Nevus Syndrome
-Cervical Cancer
-Medulloblastoma
-Basal Cell Carcinoma (BCC) - Skin
-Stomach Cancer
XPA 9q22.3 XP1, XPACGermline-Lung Cancer
-Skin Cancer
OMD 9q22.31 OSAD, SLRR2CSomatic
MIRLET7D 9q22.32 LET7D, let-7d, MIRNLET7D, hsa-let-7d-Lung Cancer
-Small Cell Lung Cancer
-Ovarian Cancer
-Pancreatic Cancer
-Prostate Cancer
-Skin Cancer
-Uterine Sarcoma
KLF4 9q31 EZF, GKLF-Bladder Cancer
-Breast Cancer
-Colorectal Cancer
-Stomach Cancer
-Uterine Sarcoma
ABCA1 9q31.1 TGD, ABC1, CERP, ABC-1, HDLDT1-Breast Cancer
-Liver Cancer
-Prostate Cancer
RAD23B 9q31.2 P58, HR23B, HHR23B-Bladder Cancer
-Breast Cancer
-Liver Cancer
-Lung Cancer
TAL2 9q32 Somatic-Ovarian Cancer
TNFSF15 9q32 TL1, TL1A, VEGI, VEGI192A-Bladder Cancer
-Breast Cancer
-Kidney Cancer
DEC1 9q32 CTS9-Breast Cancer
-Esophageal Cancer
-Lung Cancer
-Pancreatic Cancer
BRINP1 9q32-q33 DBC1, FAM5A, DBCCR1
PTGS1 9q32-q33.3 COX1, COX3, PHS1, PCOX1, PES-1, PGHS1, PTGHS, PGG/HS, PGHS-1-Colorectal Cancer
TRAF1 9q33-q34 EBI6, MGC:10353-Breast Cancer
NR5A1 9q33 ELP, SF1, FTZ1, POF7, SF-1, AD4BP, FTZF1, SPGF8, SRXY3-Adrenocortical Cancer
-Ovarian Cancer
TLR4 9q33.1 TOLL, CD284, TLR-4, ARMD10-Breast Cancer
-Colorectal Cancer
-Prostate Cancer
-Stomach Cancer
DAB2IP 9q33.1-q33.3 AIP1, AIP-1, AF9Q34, DIP1/2-Bladder Cancer
-Lung Cancer
-Prostate Cancer
CNTRL 9q33.2 FAN, CEP1, CEP110, bA165P4.1Somatic-Acute Myeloid Leukaemia
-Brain and CNS Tumours
-Myeloproliferative Disorders
PAPPA 9q33.2 PAPA, DIPLA1, PAPP-A, PAPPA1, ASBABP2, IGFBP-4ase-Acute Myeloid Leukaemia
-Cervical Cancer
-Chronic Lymphocytic Leukemia
-Haematological Malignancies
-Ovarian Cancer
PBX3 9q33.3 -Acute Lymphocytic Leukaemia (ALL)
-Acute Myeloid Leukaemia
-Leukaemia
SET 9q34 2PP2A, IGAAD, TAF-I, I2PP2A, IPP2A2, PHAPII, TAF-IBETASomatic
Translocation
-Acute Myeloid Leukaemia
-Wilms Tumour
FNBP1 9q34 FBP17Somatic-Esophageal Cancer
TSC1 9q34 LAM, TSCGermline-Kidney Cancer
-Lung Cancer
PAEP 9q34 GD, GdA, GdF, GdS, PEP, PAEG, PP14-Breast Cancer
-Endometrial Cancer
-Melanoma
-Ovarian Cancer
TRAF2 9q34 TRAP, TRAP3, MGC:45012-Breast Cancer
LCN2 9q34 24p3, MSFI, NGAL-Breast Cancer
-Esophageal Cancer
-Liver Cancer
-Pancreatic Cancer
BRD3 9q34 ORFX, RING3LSomatic-Acute Myeloid Leukaemia
NUP214 9q34.1 CAN, CAIN, N214, p250, D9S46ESomatic
Translocation
-Acute Lymphocytic Leukaemia (ALL)
-Acute Myeloid Leukaemia
FPGS 9q34.1 -Acute Lymphocytic Leukaemia (ALL)
-Colorectal Cancer
-Lung Cancer
-Lung Cancer, Non-Small Cell
ABL1 9q34.1 ABL, JTK7, p150, c-ABL, v-abl, c-ABL1, bcr/ablSomatic
Translocation
-Acute Lymphocytic Leukaemia (ALL)
-Chronic Myelogenous Leukemia
CDK9 9q34.1 TAK, C-2k, CTK1, CDC2L4, PITALRE-Breast Cancer
-Cervical Cancer
TTF1 9q34.13 TTF-1, TTF-I-Lung Cancer
-Lung Cancer, Non-Small Cell
-Small Cell Lung Cancer
-Thyroid Cancer
RALGDS 9q34.3 RGF, RGDS, RalGEFSomatic-Breast Cancer
-Cervical Cancer
-Colorectal Cancer
-Lung Cancer
-Pancreatic Cancer
NOTCH1 9q34.3 hN1, AOS5, TAN1, AOVD1Somatic
Translocation
-Acute Lymphocytic Leukaemia (ALL)
-Acute Lymphocytic Leukemia (ALL), child
-Breast Cancer
-Childhood Cancers
-Chronic Lymphocytic Leukemia
-Esophageal Cancer
-Head and Neck Cancers
-Thyroid Cancer
RXRA 9q34.3 NR2B1-Liver Cancer
-Prostate Cancer
-Retinoblastoma
RAPGEF1 9q34.3 C3G, GRF2
MIR126 9q34.3 MIRN126, miRNA126-Acute Lymphocytic Leukaemia (ALL)
-Breast Cancer
-Cervical Cancer
-Colorectal Cancer
-Lung Cancer
-Lung Cancer, Non-Small Cell
-Skin Cancer

Structural Abnormalities

Selected list of common recurrent structural abnormalities - Chromosome 9:

This is a highly selective list aiming to capture structural abnormalies which are frequesnt and/or significant in relation to diagnosis, prognosis, and/or characterising specific cancers. For a much more extensive list see the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer.

Further Resources (2 links)

Disclaimer: This site is for educational purposes only; it can not be used in diagnosis or treatment.

Cite this page: Cotterill SJ. Chromosome 9, Cancer Genetics Web: http://www.cancerindex.org/geneweb/clinkc09.htm Accessed:

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