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PTCH; Patched (Drosophila) homolog (nevoid basal cell carcinoma syndrome) (9q22.3)
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    Summary Information - PTCH
    Gene Database Entries for PTCH
    Other PTCH Related Resources
    PTCH and Nevoid Basal Cell Carcinoma Syndrome
    PTCH and Medulloblastoma
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  Summary Information

PTCH; Patched (Drosophila) homolog (nevoid basal cell carcinoma syndrome)

Location: 9q22.3
Alias: PTC

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  Gene Database Entries for PTCH

OMIM
GeneCard (Weizmann Institute)
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Human Gene Mutation Database (Cardiff, UK)
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for PTCH)

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  Other Related Resources

Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (PTCH[TI] OR PTC[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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      PTCH and Nevoid Basal Cell Carcinoma Syndrome

  • Unden AB, et al. Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: different in vivo mechanisms of PTCH inactivation Cancer Res. 1996; 56(20):4562-5    Related articles (PubMed)

  • Wicking C, et al. De novo mutations of the Patched gene in nevoid basal cell carcinoma syndrome help to define the clinical phenotype Am J Med Genet. 1997; 73(3):304-7    Related articles (PubMed)

  • Vortmeyer AO, et al. Deletion analysis of the adenomatous polyposis coli and PTCH gene loci in patients with sporadic and nevoid basal cell carcinoma syndrome-associated medulloblastoma Cancer. 1999; 85(12):2662-7    Related articles (PubMed)

  • Medline Search: ptch AND nevoid basal cell carcinoma syndrome (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Non-Melanoma Skin Cancer Genetics
    Non-Melanoma Skin Cancer : Clinical and Epidemiological Information

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  •   PTCH and Medulloblastoma

  • Zurawel RH, et al. Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma Genes Chromosomes Cancer 2000; 27(1):44-51    Related articles (PubMed)

  • Raffel C, et al. Sporadic medulloblastomas contain PTCH mutations. Cancer Res 1997; 57(5):842-5    Related articles (PubMed)

  • Vortmeyer AO, et al. Deletion analysis of the adenomatous polyposis coli and PTCH gene loci in patients with sporadic and nevoid basal cell carcinoma syndrome-associated medulloblastoma Cancer. 1999; 85(12):2662-7    Related articles (PubMed)

  • Medline Search: medulloblastoma AND ptch (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
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    Childhood Brain Tumours Genetics

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