Summary Information - BCR Gene Database Entries for BCR Other BCR Related Resources t(9;22) ABL1-BCR "Philadelphia" translocation in Leukaemia Philadelphia Chromosome in Acute Lymphoblastic Leukaemia Philadelphia Chromosome in Childhood A.L.L. Feedback / suggest a new topic for BCR
BCR; Breakpoint cluster region Location: 22q11 Aliases: BCR1, D22S11 Return to BCR Contents
Location: 22q11
Aliases: BCR1, D22S11
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OMIM GeneCard (Weizmann Institute) Atlas of Genetics and Cytogenetics in Oncology and Haematology Tumor Gene Database Swiss-Prot Locus Link UniGene GenAtlas GDB Nomenclature (search for BCR) Return to BCR Contents
Case study: 39 year old woman with acute lymphoblastic leukemia with t(9;22)(q43;q11.2) (Department of Pathology, University of Pittsburgh) ABL gene (9q34.1) Chronic Myeloid Leukaemia Leukaemia Resources Medline Search: BCR (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Search Medline for related articles (PubMed) Medline Search: cancer AND gene AND (BCR[TI] OR BCR1[TI] OR D22S11[TI]) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to BCR Contents
Chissoe SL, et al. Sequence and analysis of the human ABL gene, the BCR gene, and regions involved in the Philadelphia chromosomal translocation. Genomics 1995 May 1;27(1):67-82 Related articles (PubMed) de Klein A, et al. A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia. Nature 1982; 300(5894):765-7 Related articles (PubMed) Medline Search: leukemia AND ((ABL AND BCR AND gene) OR (Philadelphia AND chromosome)) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources Leukaemia Genetics Leukaemia : Clinical and Epidemiological Information Return to BCR Contents
Medline Search: acute lymphoblastic leukemia AND (Philadelphia OR (ABL AND BCR)) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources Acute Lymphocytic Leukaemia Genetics Acute Lymphocytic Leukaemia : Clinical and Epidemiological Information Return to BCR Contents
Heerema NA, et al. Association of chromosome arm 9p abnormalities with adverse risk in childhood acute lymphoblastic leukemia: A report from the Children's Cancer Group. Blood. 1999; 94(5):1537-44 Related articles (PubMed) Viehmann S, et al. Multiplex PCR-a rapid screening method for detection of gene rearrangements in childhood acute lymphoblastic leukemia Ann Hematol. 1999;78(4):157-62 Related articles (PubMed) Medline Search: acute lymphoblastic leukemia AND childhood AND (Philadelphia OR (ABL AND BCR)) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources Childhood Leukaemia Genetics Childhood Leukaemia : Clinical and Epidemiological Information Return to BCR Contents
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ABL gene (9q34.1)