 Summary Information
|
Location: 9q34.3
Alias: TAN1
 Return to NOTCH1 Contents
|
| Gene Database Entries for NOTCH1
|
OMIM
GeneCard (Weizmann Institute)
Swiss-Prot
Locus Link
GenAtlas
GDB
Nomenclature (search for NOTCH1)
Return to NOTCH1 Contents
|
| Other Related Resources
|
- Search Medline for related articles (PubMed)
-
- Medline Search: cancer AND gene AND (NOTCH1[TI] OR TAN1[TI]) (PubMed)
Limit search to: [Last Year] Limit search to: [Last 2 Years]
Limit search to: [Reviews]
Return to NOTCH1 Contents
|
| NOTCH1 and Cancer
|
Jeffries S, et al. Neoplastic transformation by Notch requires nuclear localization. Mol Cell Biol 2000 Jun;20(11):3928-41 Related articles (PubMed)
Ruiz-Hidalgo MJ, et al. Notch-1 expression levels in 3T3-L1 cells influence ras signaling and transformation by oncogenic ras. Int J Oncol 1999 Apr;14(4):777-83 Related articles (PubMed)
Joutel A, et al. Notch signalling pathway and human diseases. Semin Cell Dev Biol 1998 Dec;9(6):619-25 Related articles (PubMed)
Capobianco AJ, et al. Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol Cell Biol 1997 Nov;17(11):6265-73 Related articles (PubMed)
Medline Search: cancer AND (notch1 OR notch-1 OR tan-1) (PubMed)
Limit search to: [Last Year] Limit search to: [Last 2 Years]
Limit search to: [Reviews]
Return to NOTCH1 Contents
|
| NOTCH1 Truncation in T-Cell Malignancies
|
Feldman BJ, et al. A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic mice. Blood 2000 Sep 1;96(5):1906-13 Related articles (PubMed)
Hoemann CD, et al. Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice. Mol Cell Biol 2000 Jun;20(11):3831-42 Related articles (PubMed)
Girard L, et al. A full-length Notch1 allele is dispensable for transformation associated with a provirally activated truncated Notch1 allele in Moloney MuLV-infected MMTV(D)/myc transgenic mice. Oncogene 1998 Jan 29;16(4):517-22 Related articles (PubMed)
Medline Search: (leukemia OR lymphoma) AND (notch1 OR notch-1 OR tan-1) (PubMed)
Limit search to: [Last Year] Limit search to: [Last 2 Years]
Limit search to: [Reviews]
- Related Resources
 Leukaemia Genetics
Leukaemia : Clinical and Epidemiological Information
Return to NOTCH1 Contents
|
| t(7;9)(q34;q34.3) in T-Cell Acute Lymphoblastic Leukaemia
|
Ellisen LW, et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 1991 Aug 23;66(4):649-61 Related articles (PubMed)
Medline Search: leukemia AND (notch1 OR notch-1 OR tan-1) AND translocation (PubMed)
Limit search to: [Last Year] Limit search to: [Last 2 Years]
Limit search to: [Reviews]
- Related Resources
Acute Lymphocytic Leukaemia Genetics
Acute Lymphocytic Leukaemia : Clinical and Epidemiological Information
Return to NOTCH1 Contents
|
| NOTCH1 Truncation by MMTV Virus in Mouse Malignancies
|
Yanagawa S, et al. Identification of Notch1 as a frequent target for provirus insertional mutagenesis in T-cell lymphomas induced by leukemogenic mutants of mouse mammary tumor virus. J Virol 2000 Oct;74(20):9786-91 Related articles (PubMed)
Dievart A, et al. Involvement of Notch1 in the development of mouse mammary tumors. Oncogene 1999 Oct 28;18(44):5973-81 Related articles (PubMed)
Medline Search: notch1 AND virus AND cancer (PubMed)
Limit search to: [Last Year] Limit search to: [Last 2 Years]
Limit search to: [Reviews]
Return to NOTCH1 Contents
|
|
[Home] This page created: 07/11/2000 Last revised: 29/04/2003 © Copyright 1999-
|
