 Summary Information
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Location: 17q25
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| Gene Database Entries for TIMP2
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OMIM
GeneCard (Weizmann Institute)
Human Gene Mutation Database (Cardiff, UK)
Tumor Gene Database
Genbank
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for TIMP2)
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| Other Related Resources
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- Search Medline for related articles (PubMed)
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- Medline Search: cancer AND gene AND TIMP2[TI] (PubMed)
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| TIMP2 and Cancer
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Stetler-Stevenson WG, et al. Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues. J Biol Chem 1990 Aug 15;265(23):13933-8 Related articles (PubMed)
Bramhall SR, et al. Imbalance of expression of matrix metalloproteinases (MMPs) and tissue inhibitors of the matrix metalloproteinases (TIMPs) in human pancreatic carcinoma. J Pathol. 1997;182(3):347-55 Related articles (PubMed)
Medline Search: cancer AND TIMP2 (PubMed)
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| TIMP2 and Liver Cancer
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Musso O, et al. In situ detection of matrix metalloproteinase-2 (MMP2) and the metalloproteinase inhibitor TIMP2 transcripts in human primary hepatocellular carcinoma and in liver metastasis. J Hepatol. 1997;26(3):593-605. Related articles (PubMed)
Theret N, et al. Overexpression of matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-2 in liver from patients with gastrointestinal adenocarcinoma and no detectable metastasis Int J Cancer. 1997 Aug 22;74(4):426-32 Related articles (PubMed)
Medline Search: liver cancer AND TIMP2 (PubMed)
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- Related Resources
 Hepatocelular Carcinoma Genetics
Hepatocelular Carcinoma : Clinical and Epidemiological Information
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| TIMP2 and Malignant Melanoma
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Kurschat P, et al. Tissue inhibitor of matrix metalloproteinase-2 regulates matrix metalloproteinase-2 activation by modulation of membrane-type 1 matrix metalloproteinase activity in high and low invasive melanoma cell lines. J Biol Chem. 1999 Jul 23;274(30):21056-62. Related articles (PubMed)
Medline Search: malignant melanoma AND TIMP2 (PubMed)
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Melanoma Genetics
Melanoma : Clinical and Epidemiological Information
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| TIMP2 and Bladder Cancer
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Grignon DJ, et al. High levels of tissue inhibitor of metalloproteinase-2 (TIMP-2) expression are associated with poor outcome in invasive bladder cancer. Cancer Res. 1996; 56(7):1654-9. Related articles (PubMed)
Medline Search: bladder cancer AND TIMP2 (PubMed)
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Bladder Ca. Genetics
Bladder Ca. : Clinical and Epidemiological Information
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| TIMP2 and Chondrosarcoma
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Sakamoto A, et al. Expression of membrane type 1 matrix metalloproteinase, matrix metalloproteinase 2 and tissue inhibitor of metalloproteinase 2 in human cartilaginous tumors with special emphasis on mesenchymal and dedifferentiated chondrosarcoma. J Cancer Res Clin Oncol 1999;125(10):541-8 Related articles (PubMed)
Medline Search: chondrosarcoma AND TIMP2 (PubMed)
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Chondrosarcoma Genetics
Chondrosarcoma : Clinical and Epidemiological Information
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| TIMP2 and Breast Cancer
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Remacle A, et al. High levels of TIMP-2 correlate with adverse prognosis in breast cancer. Int J Cancer 2000;89(2):118-121 Related articles (PubMed)
Medline Search: breast cancer AND TIMP2 (PubMed)
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Breast Cancer Genetics
Breast Cancer : Clinical and Epidemiological Information
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| TIMP2 Expression and Lung Cancer
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Karameris A, et al. Association of expression of metalloproteinases and their inhibitors with the metastatic potential of squamous-cell lung carcinomas. A molecular and immunohistochemical study. Am J Respir Crit Care Med 1997 Dec;156(6):1930-6 Related articles (PubMed)
Medline Search: lung cancer AND timp2 (PubMed)
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Lung Cancer Genetics
Lung Cancer : Clinical and Epidemiological Information
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[Home] This page created: 10/03/2000 Last revised: 29/04/2003 © Copyright 1999-
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