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ABL2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) (1q24-q25)
ABL2 Menu

    Summary Information - ABL2
    Gene Database Entries for ABL2
    Other ABL2 Related Resources
    ABL2 - Defining Texts
    t(1;12)(q25;p13) in Acute Myeloid Leukaemia
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  Summary Information

ABL2; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

Location: 1q24-q25

Aliases: ARG, ABLL

Overview: ABL2 has close homology to the ABL proto-oncogene. It has been reported to be fused with the ETV6 gene in acute myelod leukemia with t(1;12)(q25;p13).

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  Gene Database Entries for ABL2

OMIM
GeneCard (Weizmann Institute)
Tumor Gene Database
Swiss-Prot
Locus Link (search for ABL2)
UniGene
GenAtlas
GDB
Nomenclature (search for ABL2)

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  Other Related Resources

Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (ABL2[TI] OR ARG[TI] OR ABLL[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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      ABL2 - Defining Texts

  • Kruh GD, et al. A novel human gene closely related to the abl proto-oncogene. Science 1986; 234(4783):1545-8    Related articles (PubMed)

  • Medline Search: cancer AND (abl2 OR abl-2 OR abll) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

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  •   t(1;12)(q25;p13) in Acute Myeloid Leukaemia

  • Cazzaniga G, et al. The tyrosine kinase abl-related gene ARG is fused to ETV6 in an AML-M4Eo patient with a t(1;12)(q25;p13): molecular cloning of both reciprocal transcripts. Blood 1999 Dec 15;94(12):4370-3    Related articles (PubMed)

  • Iijima Y, et al. A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation. Blood 2000 Mar 15;95(6):2126-31    Related articles (PubMed)

  • Medline Search: acute myeloid leukemia AND translocation AND (arg OR abl2) AND (etv6 OR tel) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Acute Myeloid Leukaemia Genetics
    Acute Myeloid Leukaemia : Clinical and Epidemiological Information

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