Summary Information - AF10 Gene Database Entries for AF10 Other AF10 Related Resources t(10;11) translocation in Acute Leukaemia - t(10;11) AF10-MLL translocation in Acute Leukaemia - t(10;11) AF10-CALM translocation in Acute Leukaemia Feedback / suggest a new topic for AF10
AF10; ALL1 fused gene from chromosome 10 Location: 10p12 Alias: ALL1 Return to AF10 Contents
Location: 10p12 Alias: ALL1
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OMIM GeneCard (Weizmann Institute) Swiss-Prot Locus Link GenAtlas GDB (search for AF10) Nomenclature (search for AF10) Return to AF10 Contents
Search Medline for related articles (PubMed) Medline Search: cancer AND gene AND (AF10[TI] OR ALL1[TI]) (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Return to AF10 Contents
Chaplin T, et al. A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t(10;11) translocation in acute leukemia. Blood 1995; 85(6):1435-41 Related articles (PubMed) Dreyling MH, et al. MLL and CALM are fused to AF10 in morphologically distinct subsets of acute leukemia with translocation t(10;11): both rearrangements are associated with a poor prognosis. Blood 1998; 91(12):4662-7 Related articles (PubMed) Kobayashi H, et al. Hematologic malignancies with the t(10;11) (p13;q21) have the same molecular event and a variety of morphologic or immunologic phenotypes. Genes Chromosomes Cancer 1997; 20(3):253-9 Related articles (PubMed) Medline Search: AF10 AND leukemia AND translocation AND chromosome 11 (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources Leukaemia Genetics Leukaemia : Clinical and Epidemiological Information Return to AF10 Contents
Beverloo HB, et al. Breakpoint heterogeneity in t(10;11) translocation in AML-M4/M5 resulting in fusion of AF10 and MLL is resolved by fluorescent in situ hybridization analysis. Cancer Res 1995; 55(19):4220-4 Related articles (PubMed) Medline Search: AF10 AND MLL AND leukemia AND translocation (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources MLL gene AF10 gene Leukaemia Genetics Leukaemia : Clinical and Epidemiological Information Return to AF10 Contents
Kumon K, et al. Mixed-lineage leukemia with t(10;11)(p13;q21): an analysis of AF10-CALM and CALM-AF10 fusion mRNAs and clinical features. Genes Chromosomes Cancer 1999;25(1):33-9 Related articles (PubMed) Silliman CC, et al. Alternative splicing in wild-type AF10 and CALM cDNAs and in AF10-CALM and CALM-AF10 fusion cDNAs produced by the t(10;11)(p13-14;q14-q21) suggests a potential role for truncated AF10 polypeptides. Leukemia 1998;12(9):1404-10 Related articles (PubMed) Dreyling MH, et al. The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family. Proc Natl Acad Sci USA 1996; 93(10):4804-9 Related articles (PubMed) Medline Search: AF10 AND CALM AND leukemia AND translocation (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews] Related Resources CALM gene AF10 gene Leukaemia Genetics Leukaemia : Clinical and Epidemiological Information Return to AF10 Contents
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Leukaemia Genetics