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NUP98; Nucleoporin 98kD (11p15)
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    Summary Information - NUP98
    Gene Database Entries for NUP98
    Other NUP98 Related Resources
    t(7;11)(p15;p15) in Acute Myelogenous Leukaemia
    t(7;11)(p15;p15) in Chronic Myelogenous Leukaemia
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  Summary Information

NUP98; Nucleoporin 98kD

Location: 11p15

A subset of patients with myeloid leukaemias have a t(7;11)(p15;p15) translocation fusing the NUP98 and HOXA9 genes.

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  Gene Database Entries for NUP98

OMIM
GeneCard (Weizmann Institute)
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Genbank
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for NUP98)

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  Other Related Resources

Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND NUP98[TI] (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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      t(7;11)(p15;p15) in Acute Myelogenous Leukaemia

  • Hatano Y, et al. Molecular heterogeneity of the NUP98/HOXA9 fusion transcript in myelodysplastic syndromes associated with t(7;11)(p15;p15). Br J Haematol 1999 Dec;107(3):600-4    Related articles (PubMed)

  • Kwong YL, et al. Low frequency of rearrangements of the homeobox gene HOXA9/t(7;11) in adult acute myeloid leukemia. Genes Chromosomes Cancer 1999 May;25(1):70-4    Related articles (PubMed)

  • Nakamura T, et al. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia. Nat Genet 1996 Feb;12(2):154-8    Related articles (PubMed)

  • Borrow J, et al. The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9. Nat Genet 1996 Feb;12(2):159-67    Related articles (PubMed)

  • Medline Search: acute myelogenous leukemia AND translocation AND chromosome 7 AND chromosome 11 (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Acute Myeloid Leukaemia Genetics
    Acute Myeloid Leukaemia : Clinical and Epidemiological Information

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  •   t(7;11)(p15;p15) in Chronic Myelogenous Leukaemia

  • Wong KF, et al. Chronic myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98/HOXA9 fusion. Cancer Genet Cytogenet 1999 Nov;115(1):70-2    Related articles (PubMed)

  • Kaneko Y, et al. Possible association of a new translocation, t(7;11)(p15;p15), with Ph1 chromosome-negative chronic myelogenous leukemia. Int J Cancer 1985 Dec 15;36(6):657-9    Related articles (PubMed)

  • Medline Search: chronic myelogenous leukemia AND translocation AND chromosome 7 AND chromosome 11 (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Chronic Myeloid Leukaemia Genetics
    Chronic Myeloid Leukaemia : Clinical and Epidemiological Information

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