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TPMT; Thiopurine S-methyltransferase

Location: 6p22.3

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OMIM
GeneCard (Weizmann Institute)
Human Gene Mutation Database (Cardiff, UK)
Genbank
Swiss-Prot
Locus Link (search for TPMT)
UniGene
GenAtlas
GDB
Nomenclature (search for TPMT)

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Search Medline for related articles (PubMed)

Medline Search: cancer AND gene AND TPMT[TI] (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

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Coulthard SA, et al. The relationship between thiopurine methyltransferase activity and genotype in blasts from patients with acute leukemia. Blood 1998 Oct 15;92(8):2856-62    Related articles (PubMed)

Medline Search: leukemia AND thiopurine methyltransferase (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources
Leukaemia Genetics
Leukaemia : Clinical and Epidemiological Information

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McLeod HL, et al. Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia. [Review] Leukemia 2000 Apr;14(4):567-72    Related articles (PubMed)

Relling MV, et al. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J Natl Cancer Inst 1999 Dec 1;91(23):2001-8    Related articles (PubMed)

McLeod HL, et al. Analysis of thiopurine methyltransferase variant alleles in childhood acute lymphoblastic leukaemia Br J Haematol 1999 Jun;105(3):696-700    Related articles (PubMed)

Medline Search: childhood leukemia AND thiopurine methyltransferase (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources
Childhood Leukaemia Genetics
Childhood Leukaemia : Clinical and Epidemiological Information

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