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    t(16;16)(p13q22) CBFB-MYH11 Translocation in AML
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CBFB; Core-binding factor, beta subunit

Location: 16q22.1
Alias: PEBP2b

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Medline Search: cancer AND gene AND (CBFB[TI] OR PEBP2b[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

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Castilla LH, et al. The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia. Nat Genet 1999 Oct;23(2):144-6    Related articles (PubMed)

Asou N, et al. Acute myelomonoblastic leukemia carrying the PEBP2beta/MYH11 fusion gene. Leuk Lymphoma 1998 Sep;31(1-2):81-91    Related articles (PubMed)

Costello R, et al. Detection of CBFbeta/MYH11 fusion transcripts in acute myeloid leukemia: heterogeneity of cytological and molecular characteristics. Leukemia 1997 May;11(5):644-50    Related articles (PubMed)

Liu P, et al. Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia. Science 1993 Aug 20;261(5124):1041-4    Related articles (PubMed)

Medline Search: acute myeloid leukemia AND chromosome 16 AND translocation (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources
Acute Myeloid Leukaemia Genetics
Acute Myeloid Leukaemia : Clinical and Epidemiological Information

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