Summary Information - CYP3A4
    Gene Database Entries for CYP3A4
    Other CYP3A4 Related Resources
    Cytochromes and Cyclophosphamide / Ifosfamide Activation
    CYP3A4 and Prostate Cancer
    CYP3A4 and Treatment Related Leukaemia
    Feedback / suggest a new topic for CYP3A4

CYP3A4; Cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4

Location: 7q22.1

Return to CYP3A4 Contents
 

OMIM
GeneCard (Weizmann Institute)
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for CYP3A4)

Return to CYP3A4 Contents
 

Search Medline for related articles (PubMed)

Medline Search: cancer AND gene AND CYP3A4[TI] (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Return to CYP3A4 Contents
 

Chang TK, et al. Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes. Cancer Res 1993; 53(23):5629-37    Related articles (PubMed)

Lohr M, et al. Cell therapy using microencapsulated 293 cells transfected with a gene construct expressing CYP2B1, an ifosfamide converting pancreatic carcinoma: a phase I/II study. J Mol Med 1999; 77(4):393-8    Related articles

Muller P, et al. Injection of encapsulated cells producing an ifosfamide-activating cytochrome P450 for targeted chemotherapy to pancreatic tumors. Ann N Y Acad Sci 1999; 880:337-51    Related articles (PubMed)

Aghi M, et al. Multimodal cancer treatment mediated by a replicating oncolytic virus that delivers the oxazaphosphorine/rat cytochrome P450 2B1 and ganciclovir/herpes simplex virus thymidine kinase gene therapies. Cancer Res. 1999; 59(16):3861-5    Related articles (PubMed)

Medline Search: (cytochromes OR P450) AND (ifosfamide OR cyclophosphamide) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources

Chemotherapy Resources

Return to CYP3A4 Contents
 

Ando Y, et al. Re: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. [Letter] J Natl Cancer Inst. 1999; 91(18):1587-90    Related articles

Rebbeck TR, et al. Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. J Natl Cancer Inst. 1998; 90(16):1225-9    Related articles (PubMed)

Medline Search: CYP3A4 AND prostate cancer (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Related Resources
Prostate Cancer Genetics
Prostate Cancer : Clinical and Epidemiological Information

Return to CYP3A4 Contents
 

Felix CA, et al. Association of CYP3A4 genotype with treatment-related leukemia. Proc Natl Acad Sci USA. 1998; 95(22):13176-81    Related articles

Medline Search: CYP3A4 and Treatment Related Leukaemia (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

Return to CYP3A4 Contents