 Mutated Genes and Abnormal Protein Expression
|
| Gene | Location | Topics
|
| BCL10 (
CLAP
, CIPER
)
| 1p22
|
-t(1;14)(p22;q32) in MALT B cell lymphoma
|
| BLYM | 1p32
|
|
| MUC1 (
PUM
, PEM
)
| 1q21
|
-t(1;14)(q21;q32) and MUC1 Overexpression in NHL
|
| ALK | 2p23
|
-t(2;5)(p23;q35) NPM1-ALK translocation in NHL
|
| BCL6 (
LAZ3
, ZNF51
)
| 3q27
|
-BCL6 and B-cell non-Hodgkin's lymphoma
-t(3;14)(q27;q32) in B-cell non-Hodgkin's lymphoma
|
| NPM1 (
B23
)
| 5q35
|
-t(2;5)(p23;q35) NPM1-ALK translocation in NHL
|
| IRF4 (
MUM1
, LSIRF
)
| 6p25-p23
|
-t(6;14)(p25,q32) in Lymphomas
|
| IL6 (
IFNB2
)
| 7p21
|
-IL-6 Expression in T-Cell Lymphoma
-IL-6 Expression in Indolent Lymphoma
|
| NBS1 | 8q21
|
|
| MYBL1 (
AMYB
, A-MYB
)
| 8q22
|
-MYBL1 Expression in Burkitt's lymphoma and B-ALL
|
| MYC (
CMYC
, C-MYC
)
| 8q24.12-q24.13
|
-MYC and Lymphoma
|
| FRAT2 (
GBP
)
| 10?
|
-FRAT2 Expression in T-Cell Lymphoma
|
| BMI1 | 10p13
|
|
| FRAT1 | 10q23-q24 ?
|
-FRAT1 Over-Expression in T-cell Lymphoma
|
| CD44 (
MDU3
, HA
, MDU2
)
| 11pter-p13
|
-CD44 and Non-Hodgkin's Lymphoma
|
| CCND1 (
D11S287E
, Cyclin D
, PRAD1
)
| 11q13
|
-CCND1 Overexpression in Mantle Cell Lymphoma
|
| BCL1 | 11q13.3
|
-BCL1 and Mantle Cell Lymphoma
|
| API2 (
MIHC
, cIAP2
)
| 11q22-q23
|
-t(11;18)(q21;q21) MALT1-API2 in MALT lymphomas
|
| ATM (
ATA
, ATC
)
| 11q22.3
|
-ATM and Mantle cell lymphoma
|
| LCP1 (
PLS2
)
| 13q14.1-q14.3
|
|
| TP53 (
p53
, P53
)
| 17p13.1
|
-TP53 Expression in MALT Lymphoma
|
| BIRC5 (
survivin
, SVV
, API4
)
| 17q25(?)
|
-Survivin Expression in Lymphoma
|
| MALT1 (
MLT
)
| 18q21
|
-t(11;18)(q21;q21) MALT1-API2 in MALT lymphomas
|
| BCL2 | 18q21.3
|
-BCL2 and Non-Hodgkin's Lymphoma
-t(14;18)(q32;q21) in Non-Hodgkin's Lymphoma
-BLC2 Amplification in Diffuse Large B-cell Lymphoma
-BCL2 Expression in MALT lymphoma
|
| PCNA | 20p12
|
-PCNA and Non Hodgkin's Lymphoma
|
| TIAM1 | 21q22.1
|
|
|
Non-Hodgkin's Lymphoma: Clinical and Epidemiological Resources