|Gene:||CD63; CD63 molecule|
|Aliases:||MLA1, ME491, LAMP-3, OMA81H, TSPAN30|
|Summary:||The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]|
|Databases:||OMIM, HGNC, Ensembl, GeneCard, Gene|
|Source:||NCBIAccessed: 31 August, 2019|
What does this gene/protein do?
Mouse over the terms for more detail; many indicate links which you can click for dedicated pages about the topic.
Data table showing topics related to specific cancers and associated disorders. Scope includes mutations and abnormal protein expression.
|Melanoma||CD63 and Melanoma||View Publications||0|
|Lung Cancer||CD63 and Lung Cancer||View Publications||0|
|Thyroid Cancer||CD63 and Thyroid Cancer||View Publications||0|
Note: list is not exhaustive. Number of papers are based on searches of PubMed (click on topic title for arbitrary criteria used).
Disclaimer: This site is for educational purposes only; it can not be used in diagnosis or treatment.
Cite this page: Cotterill SJ. CD63, Cancer Genetics Web: http://www.cancer-genetics.org/CD63.htm Accessed:
This page in Cancer Genetics Web by Simon Cotterill is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
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[Home] Page last revised: 31 August, 2019 Cancer Genetics Web, Established 1999