H4C9
Gene: | H4C9; H4 clustered histone 9 |
Aliases: | H4M, H4/m, H4FM, HIST1H4I |
Location: | 6p22.1 |
Summary: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015] |
Databases: | OMIM, HGNC, Ensembl, GeneCard, Gene |
Protein: | histone H4 |
Source: | NCBIAccessed: 31 August, 2019 |
Ontology: | What does this gene/protein do? Show (18) |
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HIST1H4I
OMIM, Johns Hopkin University
Referenced article focusing on the relationship between phenotype and genotype.
HIST1H4I
International Cancer Genome Consortium.
Summary of gene and mutations by cancer type from ICGC
HIST1H4I
Cancer Genome Anatomy Project, NCI
Gene Summary
HIST1H4I
COSMIC, Sanger Institute
Somatic mutation information and related details
HIST1H4I
GEO Profiles, NCBI
Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository.
Disclaimer: This site is for educational purposes only; it can not be used in diagnosis or treatment.
Cite this page: Cotterill SJ. HIST1H4I, Cancer Genetics Web: http://www.cancer-genetics.org/HIST1H4I.htm Accessed:
This page in Cancer Genetics Web by Simon Cotterill is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
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[Home] Page last revised: 31 August, 2019 Cancer Genetics Web, Established 1999