Langerhan's Cell Histiocytosis

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Langerhan's Cell Histiocytosis (13 links) Langerhan's Cell Histiocytosis (also known as Histiocytosis X) is a rare disease. It is not really a cancer, though it may behave like one in some respects. Histiocytes are normal cells found throughout the body, in this disease abnormally large numbers are found. LCH is more common in children but it is often seen in adults too. The disease will be classed as either single-system or multi-system depending on how many of the body's systems are effected. In a study of 314 people treated for LCH at the Mayo Clinic (Howarth et al, Cancer 1999;85:2278-90) 69% had single-system disease and 31% had multi-system LCH. Approximately half of those treated at Mayo were under 25 years old at diagnosis. Of people with single-system disease the system involved was bone (52%),pulmonary (lung) (40%), skin/mucous membrane (7%) and other sites (1%). Bone involvement was more common in younger patients while pulmonary involvement was mostly seen in those over 15 years old at diagnosis. Histiocytosis (Leukaemia Research Fund, UK) Anthony and Nicholas' Home Page Nicholas was diagnosed with Langerhans Cell Histiocytosis at age 2 months in 1998. The page includes progress reports and links to information about LCH. Histiocyte Society Hosted at The Texas Children's Cancer Center and Hematology Service this Web site provides details about the Histiocyte Society, information about histiocytosis etc. Histiocytosis Association of America An international partnership of parents, patients, physicians and friends in search of a cure. Includes the stories and home pages of members of the association. Histiozytosehilfe e.V. (Germany) German language site International Histiocytosis Organizations (Histiocytosis Association of America) list of histiocytosis organisations and contact information. Langerhan's Cell Histiocytosis (UK) a factsheet produced by the United Kingdom Children's Cancer Study Group and CancerBacup linked to the UKCCSG booklet "A Parent's Guide to Children's Cancers". Langerhans Cel Histiocytosei Belgium v.z.w. (Belgium) Dutch and French language site. Paediatric - Langerhans Cell Histiocytosis (Royal Marsden Hospital, UK) An on-line booklet. The Histiocytosis Association of the Netherlands Dutch language site ********** Information for Health Professionals *********** Case study: A 24 year old man with Langerhans Cell Granulomatosis (Department of Pathology, University of Pittsburgh) Merck Manual - LCH Physician's statement for Histiocytic Non-Malignant Syndromes (START, European School of Oncology) Referenced statement including sections on epidemiology, pathology, diagnosis, staging, treatment and follow-up produced by an editorial board of top European oncologists. Medline Search: Langerhan's Cell Histiocytosis (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews] Burgdorf WH, Zelger B The non-Langerhans' cell histiocytoses in childhood. Cutis 1996; 58(3):201-7    Related articles (PubMed) Back to the Menu