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People with Acquired Immunodeficiency Syndrome (AIDS) may be more susceptible to developing certain types of cancer because their body's natural defences have been weakened. Prior to the AIDS epidemic in the 1990's Kaposi's sarcoma was a relatively rare
disease usually seen only in older men or people who had organ transplants, however, increasing incidence of the disease has been associated with the spread of AIDS. Kaposi's sarcoma is a cancer that arises in the cells below the skin or in the mucous
membrane lining of the mouth, nose, and anus. Lymphomas (Hodgkin's disease and particularly non-Hodgkin's lymphoma) can also be aids-related, these are cancers of the lymphatic system (part of the immune system). Many chemotherapy drugs used to treat
cancer can suppress the immune system. Treatment for cancer in people with AIDS may need to be modified since AIDS has already weakened their immune system.
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 Aids Related Cancers (general)
- Aids Related Kaposi's Sarcoma
- Aids Related Lymphoma
- General HIV/AIDS Resources
- HIV and AIDS Malignancy Branch - NCI Division of Clinical Sciences The Branch conducts translational research on HIV infection and AIDS-related malignancies in children and adults. It is involved in basic research, preclinical studies, and clinical trials for AIDS and AIDS-related malignancies.
********** Information for Health Professionals ***********
- CancerLit: Aids Related Cancers (National Cancer Institute) On-line abstracts for health professionals. Sorted by month and year.
- AIDS Oncology Handbook (Cancer Therapy Evaluation Program, National Cancer Institute) the site includes information about related NCI programmes, clinical trials and related sites.
- AIDS Oncology Resources (Cancer Therapy Evaluation Program, USA) The site includes an AIDS Oncology Handbook, malignancies database, details of conferences, resources etc.
- Case study: A fourty four year old HIV positive man with CNS lymphoma (Department of Pathology, University of Pittsburgh)
- Mitsuyasu R Oncological complications of human immunodeficiency virus disease and hematologic consequences of their treatment. (Review) Clin Infect Dis 1999;29:35-43 Related articles (PubMed)
- Rabkin CS, Yellin F Cancer incidence in a population with a high prevalence of infection with human immunodeficiency virus type 1. J Natl Cancer Inst 1994;86:1711-6 Related articles (PubMed)
- Medline Search: AIDS and cancer (PubMed)
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See also  Sarcoma Resources
Incidence of non-Hodgkin's lymphoma has increased in parallel with the AIDS epidemic. Lymphomas affecting HIV infected people are mostly of the aggressive B-cell types (diffuse large cell, B-immunoblastic, or small non-cleaved Burkitt's / Burkitt's like
lymphoma) which are less common in non-HIV infected lymphoma patients. The HIV virus is not thought to a direct cause of lymphoma, rather it weakens the body's defences and may increase susceptibility to other infections such as the Epstein-Barr and HHV-8
viruses which are associated with these types of lymphomas.
See also Non-Hodgkin's Lymphoma
See also Hodgkin's Lymphoma
- AIDS-Map (UK) British HIV Association
- Bulletin of Experimental Treatments for AIDS (San Francisco AIDS Foundation, USA) a quarterly publication of the SFAF's Treatment Education and Support Unit with articles by leading researchers.
- The Body: an AIDS and HIV Information Resource
********** Information for Health Professionals ***********
- Centers for Disease Control - Divisions of HIV/AIDS Prevention (USA) The Web site includes information about HIV/AIDS and has details of basic science, surveillance, research into prevention and vaccines, conferences, fact sheets and other resources.
- HIV / AIDS Information Center (Journal of the American Medical Associaton) the site includes medical news, library, treatment, policy, education and prevention issues.
- National Library of Medicine - HIV/AIDS Specialist Information Services The Web site includes a searchable database of AIDS/HIV related publications including conference abstracts, tutorials, news and links.
- UNAIDS - Joint United Nations Programme on HIV/AIDS
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Cancer Types> AIDS Related