Summary Information - TMPRSS2
    Gene Database Entries for TMPRSS2
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    TMPRSS2 and Prostate Cancer
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TMPRSS2; Transmembrane protease, serine 2

Location: 21q22.3
Alias: PRSS10

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OMIM
GeneCard (Weizmann Institute)
Swiss-Prot
Locus Link
GenAtlas
GDB
Nomenclature (search for TMPRSS2)

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Search Medline for related articles (PubMed)

Medline Search: cancer AND gene AND (TMPRSS2[TI] OR PRSS10[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

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Vaarala MH, et al. The TMPRSS2 gene encoding transmembrane serine protease is overexpressed in a majority of prostate cancer patients: Detection of mutated TMPRSS2 form in a case of aggressive disease. Int J Cancer 2001;94(5):705-710    Related articles (PubMed)

Afar DE, et al. Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia. Cancer Res 2001;61(4):1686-92    Related articles (PubMed)

Lin B, et al. Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2. Cancer Res 1999;59(17):4180-4    Related articles (PubMed)

Related Resources
Prostate Cancer Genetics
Prostate Cancer : Clinical and Epidemiological Information

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