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NME2; non-metastatic cells 2, protein (NM23B) expressed in (17q21.3)
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    Summary Information - NME2
    Gene Database Entries for NME2
    Other NME2 Related Resources
    NME2 and Neuroblastoma
    NME2 and other Cancers
    Feedback / suggest a new topic for NME2


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  Summary Information

NME2; non-metastatic cells 2, protein (NM23B) expressed in

Location: 17q21.3

Aliases: NM23-H2, NM23B

Note: conflicting evidence of the role of this gene/protein in some human cancers.

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  Gene Database Entries for NME2

OMIM
GeneCard (Weizmann Institute)
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for NME2)

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  Other Related Resources

Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (NME2[TI] OR NM23-H2[TI] OR NM23B[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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      NME2 and Neuroblastoma

  • Godfried MB, et al. The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2. Oncogene 2002; 21(13):2097-101    Related articles (PubMed)

  • Leone A. et al. Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas. Oncogene 1993; 8:855-65    Related articles (PubMed)

  • Medline Search: neuroblastoma AND (NME2 OR NM23-H2) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Neuroblastoma Genetics
    Neuroblastoma : Clinical and Epidemiological Information

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  •   NME2 and other Cancers

  • Martinez JA. et al. Overexpression of nm23-H1 and nm23-H2 genes in colorectal carcinomas and loss of nm23-H1 expression in advanced tumour stages. Gut 1995; 37:712-20    Related articles (PubMed)

  • Yamaguchi A. et al. Expression of human nm23-H1 and nm23-H2 proteins in hepatocellular carcinoma. Cancer 1994; 73:2280-4    Related articles (PubMed)

  • van den Oord JJ. et al. Prognostic significance of nm23 protein expression in malignant melanoma. An immunohistochemical study. Melanoma Res 1997; 7:121-8    Related articles (PubMed)

  • Engel M, et al. High levels of nm23-H1 and nm23-H2 messenger RNA in human squamous-cell lung carcinoma are associated with poor differentiation and advanced tumor stages. Int J Cancer. 1993; 55:375-9    Related articles (PubMed)

  • Okabe-Kado J et al. Differentiation inhibitory factor Nm23 as a prognostic factor for acute myeloid leukemia. Leuk Lymphoma 1998; 32:19-28    Related articles (PubMed)

  • Medline Search: cancer AND (NME2 OR NM23-H2) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Resources by Disease Type

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