Fanconi Anaemia

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What is Fanconi Anaemia ? Fanconi Anaemia is a rare disorder found in children that involves the blood and bone marrow. The symptoms include severe aplastic anemia, hypoplasia of the bone marrow, and patchy discoloration of the skin. This is an autosomal recessive condition, affected children usually develop severe aplastic anemia by age 8 to 9 years. Treatment usually consists of bone marrow transplant. Fanconi Anaemia is not a cancer, though recent research has shown an association between Fanconi Anaemia and leukaemia. There are 8 types of Fanconi Anaemia; known as complementation groups A through to H. Some definitions: Anemia below normal levels of erythrocytes (red blood cells) Aplastic anemia anemia that is resistant to treatment; often accompanied by deficiencies of other blood cells. Hypoplasia incomplete / under development of a part of the body. Pancytopenia deficiency of all types of blood cells. Recessive (genetics) if the required allele (a type of gene) is not present in both members of a pair of chromosomes then that allele is not expressed. Menu: Fanconi Anaemia Fanconi Anaemia Organisations Other Fanconi Anaemia Web Pages About Blood and Bone Marrow Bone Marrow Transplants Molecular Biology of Fanconi Anaemia (Info. for Researchers) Anaplastic Anaemia Childhood Leukaemia Haematology Resources Fanconi Anaemia Organisations (6 links) Fanconi Anemia Research Fund, Inc. 1801 Willamette Street, Ste. 200 Eugene, OR 97401 Tel: 541-687-4658 Fax: 541-687-0548 800-828-4891 (toll free family support; US only) E-mail: info@fanconi.org Home Page: http://www.fanconi.org E-mail: fafund@rio.com Fanconi Anemia: A Handbook for Families and Their Physicians by Lynn and Dave Frohnmayer (PDF format) Association Française de la maladie de Fanconi Associazione Italiana per la Ricerca sull'Anemia di Fanconi (Italy) Deutschen Fanconi-Anämie-Hilfe e.V. European Fanconi Anemia Research Consortium Fanconi Anemia Research Fund (USA) Fanconi Canada - Canadian Fanconi Anemia Research Fund A non-profit organization which raises money for research into finding a cure and/or treatments for Fanconi Anemia. The Web site includes information about FA, news, FA family stories, and details of funded research. Back to the Menu Other Fanconi Anaemia Web Pages (9 links) See also Molecular Biology of Fanconi Anaemia FA Family Newsletter and FA Science Letter (Fanconi Anemia Research Fund, USA) PDF format Fanconi Anaemia (a brief summary of FA and links to FA sites) Fanconi Anemia (Disease outline by Jeffrey Erickson and Aaron Pletnikoff) Fanconi Anemia Home Page - Carrie's pages (A Fanconi Anemia family page) Fanconi Anemia: the Frohnmayer Family's Experience (A Fanconi Anemia family page) Fanconi's Anaemia (Leukaemia Research Fund, UK) Fanconi-Anaemia.co.uk This Web site has been set up by Roberto whose daughter was diagnosed with FA, in conjunction with other FA families in the UK. It includes information on FA, advice on dealing with FA and other resources. International Fanconi Anemia Registry The Registry is maintained by the Rockefeller University Hospital, USA. Clinical and genetic information is collected in order to learn how to optimize growth and development of affected children, and to increase understanding of FA. ********** Information for Health Professionals *********** Fanconi Anemia Mutation Database An international collaborative database co-ordinated by Rockefeller University (USA) and Guy's Hospital (UK). The site includes public and private databases, reference sequences and related links. Back to the Menu About Blood and Bone Marrow (2 links) For an introduction to blood see Medical Terminology for Cancer. More detailed information can be found on the following pages: Atlas of Haematology (Nagoya University School of Medicine, Japan) Blood Outline (Vanderbilt University Medical Center, USA) A guide to blood cells Back to the Menu This page first created on 27/08/96 after contact from a parent from Newcastle, UK.