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MTHFR; 5,10-methylenetetrahydrofolate reductase (NADPH) (1p36.3)
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    Summary Information - MTHFR
    Gene Database Entries for MTHFR
    Other MTHFR Related Resources
    MTHFR and Colon Cancer
    MTHFR and Acute Lymphoblastic Leukaemia
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  Summary Information

MTHFR; 5,10-methylenetetrahydrofolate reductase (NADPH)

Location: 1p36.3
Alias: NADPH

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  Gene Database Entries for MTHFR

OMIM
GeneCard (Weizmann Institute)
Human Gene Mutation Database (Cardiff, UK)
Swiss-Prot
Locus Link
GenAtlas
GDB
Nomenclature (search for MTHFR)

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  Other Related Resources

Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND (MTHFR[TI] OR NADPH[TI]) (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]
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      MTHFR and Colon Cancer

  • Chen J, et al. MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis. [Review] J Nutr 1999; 129(2S):560S-564S    Related articles (PubMed)

  • Ma J, et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res 1997; 57(6):1098-102    Related articles (PubMed)

  • Chen J, et al. A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer Cancer Res. 1996; 56(21):4862-4    Related articles (PubMed)

  • Medline Search: MTHFR AND cancer (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    ColoRectal Cancers Genetics
    ColoRectal Cancers : Clinical and Epidemiological Information

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  •   MTHFR and Acute Lymphoblastic Leukaemia

  • Skibola CF, et al. Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. Proc Natl Acad Sci USA. 1999; 96(22),12810-15    Related articles

  • Nowak-Gottl U, et al. Prospective evaluation of the thrombotic risk in children with acute lymphoblastic leukemia carrying the MTHFR TT 677 genotype, the prothrombin G20210A variant, and further prothrombotic risk factors. Blood 1999; 93(5):1595-9    Related articles (PubMed)

  • Medline Search: MTHFR AND leukemia (PubMed)   Limit search to: [Last Year]  Limit search to: [Last 2 Years]   Limit search to: [Reviews]

    Related Resources
    Acute Lymphocytic Leukaemia Genetics
    Acute Lymphocytic Leukaemia : Clinical and Epidemiological Information

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